Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747065 | 0.84 | LIPE (0.40) | ALDH1A1HSD17B10NTSR1MAPTSMN1; SMN2 | |
| SCHEMBL4749965 | 0.80 | KDM4E (0.43) | ALDH1A1HSD17B10MAPK1KMT2AKDM4E | |
| SCHEMBL4749923 | 0.79 | KDM4E (0.44) | ALDH1A1HSD17B10MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL4746294 | 0.78 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL4749360 | 0.78 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1HSD17B10MAPK1KMT2A | |
| SCHEMBL4749356 | 0.76 | KDM4E (0.42) | ALDH1A1HSD17B10MAPK1KMT2AKDM4E | |
| SCHEMBL4787866 | 0.75 | KDM4E (0.41) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL4747050 | 0.74 | KDM4E (0.52) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL4749260 | 0.71 | CCNC (0.38) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL4746545 | 0.69 | ME2 (0.44) | ALDH1A1MAPTSMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |