Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | CAMK1D | Q8IU85 | 4/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.37 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749923 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4746294 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL4749360 | 0.78 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD17B10HPGDPRKDC | |
| SCHEMBL4749965 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL4749356 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDPRKDC | |
| SCHEMBL4787866 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4747065 | 0.73 | LIPE (0.40) | KDM4EALDH1A1HSD17B10HPGDKCNH2 | |
| SCHEMBL4069470 | 0.70 | MAOA (0.37) | KDM4E | |
| SCHEMBL4746545 | 0.69 | ME2 (0.44) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4749260 | 0.69 | CCNC (0.38) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123756-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTON TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |