Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754018 | 0.95 | LMNA (0.41) | ALDH1A1LMNAMAPK10KDM4EUSP2 | |
| SCHEMBL4786661 | 0.80 | KDM4E (0.40) | ALDH1A1LMNAKDM4EDRD2SLC6A4 | |
| SCHEMBL4750809 | 0.78 | DRD2 (0.44) | ALDH1A1LMNAKDM4EHTR1AHTR7 | |
| SCHEMBL4750506 | 0.71 | AKT1 (0.36) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL4752472 | 0.70 | HTR1A (0.53) | HTR1AHTR7DRD2HTR2A | |
| SCHEMBL4908879 | 0.70 | HTR7 (0.50) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL4752410 | 0.69 | HTR2A (0.49) | HTR1ADRD2HTR2A | |
| SCHEMBL4753185 | 0.68 | DRD2 (0.51) | HTR1AHTR7DRD2SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL4787868 | 0.68 | DRD2 (0.50) | LMNAUSP2HTR1AHTR7DRD2 | |
| SCHEMBL4789463 | 0.67 | PPARG (0.44) | ALDH1A1HTR1AHTR7DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |