Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751067 | 0.86 | HTR7 (0.47) | HTR1AALDH1A1SMN1; SMN2ABCB1HTR4 | |
| SCHEMBL4752802 | 0.84 | ALDH1A1 (0.41) | HTR1AALDH1A1SMN1; SMN2ABCB1HTR4 | |
| SCHEMBL4908879 | 0.83 | HTR7 (0.50) | HTR1AABCB1HTR7DRD2HTR2A | |
| SCHEMBL4788339 | 0.82 | KCNH2 (0.50) | ABCB1HTR4SIGMAR1HTR2A | |
| SCHEMBL4754299 | 0.80 | ADRA1A (0.41) | HTR1AALDH1A1SMN1; SMN2ABCB1HTR7 | |
| Hydrochloric Acid SCHEMBL4788931 | 0.76 | GAA (0.53) | MAPTALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4863289 | 0.71 | ALDH1A1 (0.41) | HTR1AMAPTALDH1A1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL4789017 | 0.70 | KCNH2 (0.49) | ABCB1SIGMAR1HTR2A | |
| SCHEMBL314513 | 0.70 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL11810344 | 0.70 | HTR2A (0.62) | HTR1AMAPTALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |