Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752802 | 0.96 | ALDH1A1 (0.41) | ADRA1AHTR2AHTR1AHTR7DRD2 | |
| SCHEMBL4863289 | 0.83 | ALDH1A1 (0.41) | ADRA1AHTR2AHTR1ADRD2ALDH1A1 | |
| SCHEMBL4754290 | 0.80 | HTR1A (0.50) | HTR2AHTR1AHTR7DRD2ALDH1A1 | |
| SCHEMBL4788339 | 0.74 | KCNH2 (0.50) | HTR2AABCB1 | |
| SCHEMBL4908879 | 0.73 | HTR7 (0.50) | HTR2AHTR1AHTR7DRD2ABCB1 | |
| SCHEMBL12969072 | 0.70 | HTR6 (0.58) | ADRA1AHTR2AHTR1AHTR7DRD2 | |
| SCHEMBL28496894 | 0.69 | KMT2A (0.39) | HTR2AALDH1A1 | |
| SCHEMBL4754289 | 0.69 | FFAR4 (0.39) | HTR2AALDH1A1FFAR4 | |
| SCHEMBL28978441 | 0.68 | DHFR (0.40) | HTR2AHTR1AALDH1A1 | |
| SCHEMBL4753309 | 0.67 | NPC1 (0.37) | HTR2AHTR1AALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |