Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752802 | 0.87 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTR1AHTR1BADRA1D | |
| SCHEMBL4751067 | 0.85 | HTR7 (0.47) | ALDH1A1SMN1; SMN2HTR1ALMNAMEN1 | |
| SCHEMBL4754299 | 0.83 | ADRA1A (0.41) | ALDH1A1SMN1; SMN2HTR1AHTR1BADRA1D | |
| SCHEMBL4789257 | 0.72 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2HTR1ALMNAMEN1 | |
| SCHEMBL4754290 | 0.71 | HTR1A (0.50) | ALDH1A1SMN1; SMN2HTR1ALMNAHTR2A | |
| SCHEMBL4753368 | 0.70 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2FFAR4LMNAMEN1 | |
| SCHEMBL4751070 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2FFAR4LMNAMEN1 | |
| SCHEMBL4751068 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2FFAR4LMNAMEN1 | |
| SCHEMBL4750825 | 0.69 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2FFAR4LMNAMEN1 | |
| SCHEMBL4751039 | 0.69 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2FFAR4LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |