Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.30 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459486 | 0.91 | LCK (0.48) | LCKFYNSERPINE1ALDH1A1PTPN1 | |
| SCHEMBL2952944 | 0.90 | LCK (0.47) | LCKFYNSERPINE1ALDH1A1PTPN1 | |
| SCHEMBL6274784 | 0.85 | LCK (0.61) | LCKFYNSERPINE1ALDH1A1PTPN1 | |
| SCHEMBL17780858 | 0.84 | LCK (0.59) | LCKFYNSERPINE1ALDH1A1PTPN1 | |
| SCHEMBL258409 | 0.79 | LCK (0.61) | LCKFYNALDH1A1CA1CA2 | |
| SCHEMBL13520460 | 0.79 | LCK (0.46) | LCKFYNSERPINE1ALDH1A1CA1 | |
| Potassium Ion SCHEMBL28394777 | 0.78 | LCK (0.59) | LCKFYNALDH1A1CA1CA2 | |
| Lithium Ion SCHEMBL28391984 | 0.78 | LCK (0.59) | LCKFYNALDH1A1CA1CA2 | |
| SCHEMBL1331221 | 0.77 | LCK (0.47) | LCKFYNALDH1A1CA1CA2 | |
| SCHEMBL28370074 | 0.77 | SERPINE1 (0.43) | LCKFYNSERPINE1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-220503410-U | Pile fabric | 株式会社钟化 | 2024-02-20 | — | — | CN | disclosed |
| US-11314179-B2 | Polyester resin, method for producing polyester resin, and toner using said polyester resin | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-04-26 | — | — | US | disclosed |
| EP-3296341-B1 | POLYESTER RESIN, METHOD FOR PRODUCING POLYESTER RESIN, AND TONER USING SAID POLYESTER RESIN | MITSUBISHI CHEM CORP (JP) | 2019-11-06 | — | — | EP | disclosed |
| EP-3296341-A1 | POLYESTER RESIN, METHOD FOR PRODUCING POLYESTER RESIN, TONER USING SAID POLYESTER RESIN | Mitsubishi Chemical Corporation (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-20180067412-A1 | POLYESTER RESIN, METHOD FOR PRODUCING POLYESTER RESIN, AND TONER USING SAID POLYESTER RESIN | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-03-08 | — | — | US | disclosed |
| JP-2008115244-A | METHOD FOR PRODUCING COPOLYESTER | TOYOBO CO LTD | 2008-05-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11314179-B2 | Polyester resin, method for producing polyester resin, and toner using said polyester resin | GRHPR, GLRA1, TECR | CA1 1859/4885CA2 2001/4885LCK 3411/4885 |
| US-20180067412-A1 | POLYESTER RESIN, METHOD FOR PRODUCING POLYESTER RESIN, AND TONER USING SAID POLYESTER RESIN | HNRNPR, TECR, PUF60 | CA1 3818/4885CA2 4049/4885LCK 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.