SCHEMBL4761655

SCHEMBL4761655

COCCOCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
PSMB8 P28062 2/20 0.32
PSMB5 P28074 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL916010 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL589886 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL14134551 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL588927 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL9917631 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL24974550 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL12081887 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL22444953 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL21224008 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL31671113 1.00 HPGD (0.40) HPGDHTTSMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025078841-A2 ANTIBODIES, CONJUGATES, AND USES THEREOF ANTIKOR BIOPHARMA LIMITED (GB) 2025-04-17 WO disclosed
WO-2025064842-A1 DIHYDROPHENANTHRENE (DHP) BRIDGED DYES FOR USE IN FLOW CYTOMETRY BECKMAN COULTER, INC. (US) 2025-03-27 WO disclosed
US-20240254567-A1 DIAMOND MAGNETOMETRY DETECTION OF BIOLOGICAL TARGETS COLUMBUS NANOWORKS, INC. (US) 2024-08-01 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20240091315-A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME AMUNIX PHARMACEUTICALS, INC. 2024-03-21 US disclosed
WO-2024025396-A1 NOVEL AURISTATIN PRECURSOR DRUG 주식회사 레고켐 바이오사이언스 2024-02-01 WO disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
US-20080318917-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS GALERA THERAPEUTICS, LLC 2008-12-25 US disclosed
US-7432330-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
US-7432331-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
US-20080214439-A1 AMINO ACID SUBSTITUTED MOLECULES ALLOZYNE, INC. (US) 2008-09-04 US disclosed
US-20080200641-A1 AMINO ACID SUBSTITUTED MOLECULES ALLOZYNE, INC. (US) 2008-08-21 US disclosed
US-20080096819-A1 Amino acid substituted molecules ALLOZYNE, INC. (US) 2008-04-24 US disclosed
US-7318932-B2 Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2008-01-15 US disclosed
US-20070166384-A1 Methods , composition and preparations for delivery of immune response modifiers 3M INNOVATIVE PROPERTIES COMPANY 2007-07-19 US disclosed
US-7196112-B2 Cell adhesion inhibitors BIOGEN IDEC MA INC. (US) 2007-03-27 US disclosed
US-20070066533-A1 Cell adhesion inhibitors LEE WEN-CHERNG 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080318917-A1 POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS SOD1, SOD3, CAT HPGD 122/4885HTT 1383/4885SMN1; SMN2 60/4885
US-20080096819-A1 Amino acid substituted molecules BCAT2, DNPEP, PTMS HPGD 4213/4885HTT 1014/4885SMN1; SMN2 4593/4885
US-20080214439-A1 AMINO ACID SUBSTITUTED MOLECULES BCAT2, DNPEP, PTMS HPGD 4213/4885HTT 1014/4885SMN1; SMN2 4593/4885
US-20070066533-A1 Cell adhesion inhibitors VCAM1, EPCAM, ICAM1 HPGD 3620/4885HTT 3740/4885SMN1; SMN2 4336/4885
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT HPGD 1080/4885HTT 2860/4885SMN1; SMN2 95/4885
US-20080200641-A1 AMINO ACID SUBSTITUTED MOLECULES BCAT2, DNPEP, PTMS HPGD 4213/4885HTT 1014/4885SMN1; SMN2 4593/4885
US-20070166384-A1 Methods , composition and preparations for delivery of immune response modifiers TLR3, MYD88, IFNG HPGD 660/4885HTT 4298/4885SMN1; SMN2 1625/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT HPGD 1080/4885HTT 2860/4885SMN1; SMN2 95/4885
US-20240091315-A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME XPA, TXLNA, NGLY1 HPGD 2116/4885HTT 525/4885SMN1; SMN2 1489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.