Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.47 |
| ▸ | RELA | Q04206 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4768713 | 0.94 | SLC2A1 (0.49) | SLC2A1APPCHRNA7HTR3AHTR3E | |
| SCHEMBL4774628 | 0.80 | TMPRSS2 (0.61) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4768583 | 0.79 | TMPRSS2 (0.62) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4768475 | 0.79 | MEN1 (0.49) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4770901 | 0.78 | HRH3 (0.56) | CHRNA7NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL4794145 | 0.78 | MAPT (0.53) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4768190 | 0.77 | NPC1 (0.67) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4771567 | 0.77 | ROCK2 (0.46) | CHRNA7NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL4775002 | 0.77 | RAB9A (0.53) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5823896 | 0.77 | HRH3 (0.54) | NPC1RAB9ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |