Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | EIF4A1 | P60842 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779671 | 0.89 | EIF4A1 (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5EIF4A1 | |
| SCHEMBL4779677 | 0.88 | EIF4A1 (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5EIF4A1 | |
| SCHEMBL4776706 | 0.87 | PLA2G2A (0.42) | PLA2G2APLA2G10PLA2G1BPLA2G5CXCR2 | |
| SCHEMBL4774611 | 0.85 | LTB4R (0.47) | EIF4A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4776218 | 0.82 | CYP19A1 (0.42) | EIF4A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4774562 | 0.76 | CYP19A1 (0.42) | MAPTMEN1KMT2ACYP19A1CYP11B1 | |
| SCHEMBL4776697 | 0.76 | HRH2 (0.37) | PLA2G2APLA2G10PLA2G1BPLA2G5MAPT | |
| SCHEMBL4776700 | 0.74 | HRH2 (0.42) | PLA2G2APLA2G10PLA2G1BPLA2G5MAPT | |
| SCHEMBL4774672 | 0.71 | NOS3 (0.43) | MAPTMEN1KMT2ARAB9ALTB4R | |
| SCHEMBL4779650 | 0.69 | MAPT (0.46) | EIF4A1MAPTMEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |