Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 5/20 | 0.37 |
| ▸ | FNTB | P49356 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775914 | 1.00 | ALOX15 (0.41) | ALOX15ALDH1A1KMT2AFNTAFNTB | |
| SCHEMBL5074186 | 0.85 | ALOX15 (0.53) | ALOX15ALDH1A1KMT2AFNTAFNTB | |
| SCHEMBL10323527 | 0.85 | ALOX15 (0.53) | ALOX15ALDH1A1KMT2AFNTAFNTB | |
| SCHEMBL4772516 | 0.85 | ALOX15 (0.53) | ALOX15ALDH1A1KMT2AFNTAFNTB | |
| SCHEMBL9242251 | 0.82 | — | — | |
| SCHEMBL2616621 | 0.82 | — | — | |
| SCHEMBL9242249 | 0.82 | — | — | |
| SCHEMBL811389 | 0.79 | TSHR (0.39) | ALDH1A1FNTAFNTBKDM4EATM | |
| SCHEMBL22917083 | 0.76 | LMNA (0.38) | ALOX15ALDH1A1FNTAFNTBPOLB | |
| SCHEMBL13191195 | 0.75 | TSHR (0.54) | ALDH1A1KMT2AKDM4EATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879902-B1 | COMPOSITION COMPRISING ONE OR MORE LYCOPHYLL DERIVATIVES | CARDAX PHARMA INC (US) | 2020-01-08 | — | — | EP | disclosed |
| US-7435861-B2 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMACEUTICALS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20080221377-A1 | Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates | CARDAX PHARMACEUTICALS, INC. | 2008-09-11 | — | — | US | disclosed |
| EP-1879902-A2 | METHODS FOR SYNTHESIS OF CAROTENOIDS, INCLUDING ANALOGS, DERIVATIVES, AND SYNTHETIC AND BIOLOGICAL INTERMEDIATES | Hawaii Biotech, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007147163-A2 | COMPOSITIONS COMPRISING CAROTENOID ANALOGS OR DERIVATIVES AND METHODS FOR SYNTHESIS | CARDAX PHARMACEUTICALS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-7247752-B2 | Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin | CARDAX PHARMACEUTICALS, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-20060293545-A1 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMA, INC. | 2006-12-28 | — | — | US | disclosed |
| WO-2006119125-A2 | METHODS FOR SYNTHESIS OF CAROTENOIDS, INCLUDING ANALOGS, DERIVATIVES, AND SYNTHETIC AND BIOLOGICAL INTERMEDIATES | CARDAX PHARMACEUTICALS, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060183947-A1 | Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin | CARDAX PHARMA, INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060183185-A1 | Method for the synthesis of astaxanthin | CARDAX PHARMACEUTICALS, INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060178538-A1 | Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-08-10 | — | — | US | disclosed |
| US-20060167319-A1 | Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-07-27 | — | — | US | disclosed |
| US-20060155150-A1 | Methods for the synthesis of lutein | CARDAX PHARMACEUTICALS, INC. | 2006-07-13 | — | — | US | disclosed |
| US-20060111580-A1 | Methods for the synthesis of chiral dihydroxy ketone intermediates useful for the chiral synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-05-25 | — | — | US | disclosed |
| US-20060088905-A1 | Methods for the synthesis of zeazanthin | CARDAX PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
| US-20060088904-A1 | Methods for the synthesis of astaxanthin | CARDAX PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
| WO-2006039685-A2 | METHODS FOR SYNTHESIS OF CHIRAL INTERMEDIATES OF CAROTENOIDS, CAROTENOID ANALOGS, AND CAROTENOID DERIVATIVES | HAWAII BIOTECH, INC. (US) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060088904-A1 | Methods for the synthesis of astaxanthin | HSD17B7, CYP51A1, HSD11B1 | ALOX15 159/4885ALDH1A1 287/4885KMT2A 964/4885 |
| US-20060293545-A1 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | TXNRD2, TXN2, TXNRD1 | ALOX15 35/4885ALDH1A1 2064/4885KMT2A 4392/4885 |
| US-20080221377-A1 | Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates | HCCS, SQOR, CBR3 | ALOX15 38/4885ALDH1A1 1671/4885KMT2A 3959/4885 |
| US-20060178538-A1 | Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids | HSD17B7, DHPS, DHCR7 | ALOX15 108/4885ALDH1A1 327/4885KMT2A 1183/4885 |
| US-20060167319-A1 | Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids | DHPS, HSD17B7, COASY | ALOX15 67/4885ALDH1A1 436/4885KMT2A 1227/4885 |
| US-20060155150-A1 | Methods for the synthesis of lutein | LSS, DHPS, CYP51A1 | ALOX15 83/4885ALDH1A1 442/4885KMT2A 626/4885 |
| US-20060183947-A1 | Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin | DHCR7, HSD17B7, HSD11B1 | ALOX15 75/4885ALDH1A1 242/4885KMT2A 1057/4885 |
| US-20060088905-A1 | Methods for the synthesis of zeazanthin | DHPS, CYP51A1, HSD17B7 | ALOX15 110/4885ALDH1A1 667/4885KMT2A 406/4885 |
| US-20060111580-A1 | Methods for the synthesis of chiral dihydroxy ketone intermediates useful for the chiral synthesis of carotenoids | DHPS, DHCR7, HSD17B7 | ALOX15 208/4885ALDH1A1 374/4885KMT2A 1226/4885 |
| US-20060183185-A1 | Method for the synthesis of astaxanthin | SQLE, HSD17B7, CYP51A1 | ALOX15 66/4885ALDH1A1 377/4885KMT2A 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.