Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840971 | 0.87 | ALDH1A1 (0.47) | GLO1ALDH1A1LMNAHTTPOLB | |
| SCHEMBL4777634 | 0.85 | SLC40A1 (0.47) | GLO1HPGDCYP2C9CYP2C19PGR | |
| SCHEMBL4780514 | 0.84 | GLO1 (0.41) | GLO1ALDH1A1LMNAHTTPOLB | |
| SCHEMBL4781821 | 0.82 | SLC40A1 (0.49) | GLO1LMNAMAPTNPSR1MEN1 | |
| SCHEMBL4780017 | 0.82 | KAT6A (0.39) | ALDH1A1HTTHSD17B10PGREGFR | |
| SCHEMBL4779121 | 0.80 | KEAP1 (0.45) | GLO1ALDH1A1LMNAHTTPOLB | |
| SCHEMBL4727568 | 0.77 | GFER (0.43) | GLO1ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL4775751 | 0.69 | SLC40A1 (0.44) | GLO1HPGDCYP2C9CYP2C19MAPT | |
| SCHEMBL14084356 | 0.68 | BRD4 (0.35) | ALDH1A1POLBHPGDCYP2C9CYP2C19 | |
| SCHEMBL4781338 | 0.68 | SLC40A1 (0.48) | ALDH1A1LMNAHTTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | claimed |