Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784868 | 0.75 | PLD2 (0.42) | CHRM2CHRM3OPRM1OPRK1ADRA1A | |
| SCHEMBL4783965 | 0.74 | CHRM2 (0.44) | CHRM2CHRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL3728528 | 0.71 | ALDH1A1 (0.41) | CHRM2CHRM3OPRM1OPRK1ACHE | |
| SCHEMBL4826946 | 0.70 | OPRM1 (0.39) | CHRM2CHRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL3728165 | 0.70 | OPRM1 (0.39) | CHRM2CHRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL4965590 | 0.68 | DCUN1D1 (0.58) | — | |
| SCHEMBL3663968 | 0.68 | NSD2 (0.34) | — | |
| SCHEMBL4783181 | 0.66 | CHRM1 (0.44) | CHRM2CHRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL3727160 | 0.65 | RORC (0.38) | KCNH2 | |
| SCHEMBL1835272 | 0.63 | OPRM1 (0.50) | CHRM2CHRM3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |