Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methanesulfonamide SCHEMBL4804172 | 1.00 | CA1 (0.53) | CA1ALDH1A1KDM4ETSHRCA2 | |
| Sulfamide SCHEMBL29026073 | 0.90 | ALDH1A1 (0.55) | CA1ALDH1A1KDM4ETSHRCA2 | |
| Ethanesulfonic Acid Amide SCHEMBL4800715 | 0.81 | ALDH1A1 (0.48) | CA1ALDH1A1KDM4ETSHRCA2 | |
| SCHEMBL27617593 | 0.80 | CA1 (0.48) | CA1ALDH1A1KDM4ETSHRCA2 | |
| SCHEMBL2005577 | 0.79 | CA2 (0.56) | CA1ALDH1A1KDM4ETSHRCA2 | |
| SCHEMBL9482520 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TSHRRAPGEF4TPMTSELL | |
| SCHEMBL8536578 | 0.77 | ALDH1A1 (0.63) | CA1ALDH1A1KDM4ETSHRCA2 | |
| SCHEMBL841739 | 0.76 | ALDH1A1 (0.44) | CA1ALDH1A1KDM4ETSHRCA2 | |
| Sulfuric Acid SCHEMBL6214534 | 0.76 | ALDH1A1 (0.50) | CA1ALDH1A1KDM4ETSHRCA2 | |
| SCHEMBL27310696 | 0.76 | ALDH1A1 (0.44) | CA1ALDH1A1KDM4ETSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414154-B2 | Polyamine compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-20050101676-A1 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-12 | — | — | US | disclosed |
| WO-2005014524-A2 | AMINO THIOL COMPOUNDS AND COMPOSITIONS FOR USE IN CONJUNCTION WITH CANCER THERAPY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20050027016-A1 | Polyamine compounds and compositions for use in conjection with cancer therapy | FAHL KATHLEEN L (US) | 2005-02-03 | — | — | US | disclosed |
| EP-1478618-A1 | POLYAMINE COMPOUNDS AND COMPOSITIONS FOR USE IN CONJUNCTION WITH CANCER THERAPY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040225021-A1 | Polyamine compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2004-11-11 | — | — | US | disclosed |
| US-20030185778-A1 | Polyamine compounds and compositions for use in conjunction with cancer therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-10-02 | — | — | US | disclosed |
| WO-2003066572-A1 | POLYAMINE COMPOUNDS AND COMPOSITIONS FOR USE IN CONJUNCTION WITH CANCER THERAPY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040225021-A1 | Polyamine compounds and compositions for use in conjunction with cancer therapy | SRM, SMS, HNMT | CA1 1516/4885ALDH1A1 926/4885KDM4E 1966/4885 |
| US-20050101676-A1 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | SRM, MGMT, AADAT | CA1 1291/4885ALDH1A1 692/4885KDM4E 2612/4885 |
| US-20050027016-A1 | Polyamine compounds and compositions for use in conjection with cancer therapy | SRM, SMS, SMOX | CA1 1081/4885ALDH1A1 1265/4885KDM4E 2972/4885 |
| US-20030185778-A1 | Polyamine compounds and compositions for use in conjunction with cancer therapy | SRM, SMS, HNMT | CA1 1516/4885ALDH1A1 926/4885KDM4E 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.