Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540769 | 0.92 | SERPINE1 (0.48) | MC4RHPGDTRPM8ALDH1A1TSHR | |
| SCHEMBL24677538 | 0.91 | CYP3A4 (0.47) | MC4RHPGDTRPM8ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29868258 | 0.90 | CYP3A4 (0.47) | MC4RHPGDTRPM8ALDH1A1TSHR | |
| SCHEMBL4886347 | 0.89 | SERPINE1 (0.59) | HPGDTRPM8ALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL31448505 | 0.89 | ALDH1A1 (0.55) | HPGDTRPM8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15133430 | 0.89 | ALDH1A1 (0.55) | HPGDTRPM8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24540254 | 0.88 | TAAR1 (0.54) | MC4RTRPM8CYP2C19EPHX1NPSR1 | |
| SCHEMBL1629039 | 0.88 | TAAR1 (0.54) | MC4RTRPM8CYP2C19EPHX1NPSR1 | |
| SCHEMBL3392794 | 0.88 | TAAR1 (0.54) | MC4RTRPM8CYP2C19EPHX1NPSR1 | |
| SCHEMBL24677412 | 0.88 | TRPM8 (0.50) | HPGDTRPM8ALDH1A1SMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240223-A1 | ABSORBENT ARTICLE COMPRISING LOTION COMPOSITION COMPRISING A COOLING AGENT | PROCTER & GAMBLE COMPANY, THE | 2009-09-24 | — | — | US | disclosed |
| US-20080300314-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-04 | — | — | US | disclosed |
| US-7417048-B2 | Aryl-substituted derivatives of cycloalkyl and branched chain alkyl carboxylic acids useful as antinociceptive drugs for peripheral targets | WEI EDWARD T | 2008-08-26 | — | — | US | disclosed |
| US-7414152-B2 | e. g. N-(4-cyanomethylphenyl) p-menthanecarboxamide; cooling agent in cosmetics and food industries; with additional cooling compound such as menthol, menthone, isopulegol | GIVAUDAN, SA (CH) | 2008-08-19 | — | — | US | disclosed |
| US-20070053834-A1 | Radioligands for the TRP-M8 receptor and methods therewith | WEI EDWARD T | 2007-03-08 | — | — | US | disclosed |
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | WEI EDWARD T (US) | 2005-08-25 | — | — | US | disclosed |
| US-20050159394-A1 | Aryl-substituted derivatives of cycloalkyl and branched chain alkyl carboxylic acids useful as antinociceptive drugs for peripheral targets | WEI EDWARD T (US) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187211-A1 | N-arylsalkyl-carboxamide compositions and methods | OPRL1, TRPV1, TRPA1 | MC4R 1478/4885HPGD 1226/4885TRPM8 13/4885 |
| US-20070053834-A1 | Radioligands for the TRP-M8 receptor and methods therewith | GPR68, TRPM8, OPRL1 | MC4R 213/4885HPGD 4139/4885TRPM8 2/4885 |
| US-20080300314-A1 | Cooling Compounds | TAS2R42, TAS2R4, TAS2R41 | MC4R 84/4885HPGD 1148/4885TRPM8 73/4885 |
| US-20050159394-A1 | Aryl-substituted derivatives of cycloalkyl and branched chain alkyl carboxylic acids useful as antinociceptive drugs for peripheral targets | OPRL1, OPRK1, OPRD1 | MC4R 430/4885HPGD 1412/4885TRPM8 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.