Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | BCR | P11274 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | MGAM | O43451 | 6/20 | 0.41 |
| ▸ | SI | P14410 | 6/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112190 | 0.84 | ALDH1A1 (0.48) | GAASCN8AHTR1AESR2BRD4 | |
| SCHEMBL4815947 | 0.81 | HSD17B1 (0.51) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL3182619 | 0.80 | RXRA (0.53) | — | |
| SCHEMBL4813636 | 0.77 | KMT2A (0.50) | ESR1GAAESR2KDM4EALDH1A1 | |
| SCHEMBL3398525 | 0.77 | HTR1A (0.58) | GAAHTR1ABRD4KDM4EALDH1A1 | |
| SCHEMBL19956101 | 0.76 | NR1I2 (0.41) | GAABRD4KDM4EALDH1A1GLA | |
| SCHEMBL3182651 | 0.74 | MGAM (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL25193508 | 0.73 | HTR1A (0.44) | GAAHTR1ABRD4KDM4EALDH1A1 | |
| SCHEMBL10358895 | 0.73 | SCN4A (0.49) | HTR1ABRD4KDM4EMAPTHPGD | |
| SCHEMBL7044002 | 0.73 | HTR1A (0.44) | GAAHTR1ABRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | ESR1 832/4885ABL1 1998/4885ABCB1 1436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.