Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 13/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 13/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112190 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1ESR2 | |
| SCHEMBL4814971 | 0.81 | ESR1 (0.45) | KDM4EALDH1A1ESR2ESR1 | |
| SCHEMBL4811287 | 0.79 | MRGPRX4 (0.51) | ALDH1A1 | |
| SCHEMBL515980 | 0.77 | ALDH1A1 (0.61) | CYP3A4CYP2C9CYP2D6KDM4EALDH1A1 | |
| SCHEMBL7346114 | 0.75 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4818369 | 0.74 | RAB9A (0.53) | CYP3A4CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL3398525 | 0.73 | HTR1A (0.58) | KDM4EALDH1A1 | |
| Alcohol SCHEMBL9461730 | 0.72 | HSD17B1 (0.68) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL14041001 | 0.71 | HSD17B1 (0.71) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| Alcohol SCHEMBL23879308 | 0.70 | HSD17B1 (0.65) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078184-A1 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | ADRB2, ADRA2A, ADRA1A | HSD17B1 520/4885HSD17B2 370/4885CYP3A4 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.