Mannose 6-Phosphate

Mannose 6-Phosphate

SCHEMBL48152

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(=O)([O-])[O-].[Na+].[Na+]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Mannose 6-Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.52
PGD P52209 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannose 6-Phosphate SCHEMBL28885847 1.00 MPI (0.52) MPIPGD
Mannose 6-Phosphate SCHEMBL2387370 1.00 MPI (0.52) MPIPGD
Mannose 6-Phosphate SCHEMBL21632784 1.00 MPI (0.52) MPIPGD
Mannose 6-Phosphate SCHEMBL9231707 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693684 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693687 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693710 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693713 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL9234969 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693697 0.98 MPI (0.50) MPIPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122032323-A Sodium glucose phosphate modified nanofiltration membrane and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-15 CN claimed
CN-119263766-A White surface gypsum and preparation method and application thereof 山东汉诺宝嘉新材料科技有限公司 2025-01-07 CN claimed
CN-117965679-A G6PD enzyme activity detection kit and preparation method thereof 深圳市亿立方生物技术有限公司 2024-05-03 CN claimed
CN-114920765-B Aryl boric acid substituted cationic porphyrin array sensor and preparation method and application thereof 南京农业大学 2024-02-06 CN claimed
CN-117451888-A Method for detecting atherosclerosis disease glycometabolism marker based on liquid chromatography-mass spectrometry 重庆医科大学 2024-01-26 CN claimed
CN-114505064-B Synthesis method and application of manganese-doped zinc sulfide quantum dot of glucose-6-phosphate 常州磐诺仪器有限公司 2023-12-22 CN claimed
CN-115166131-A Method for detecting in-vitro DNA adduct catalyzed by drug metabolizing enzyme through single-molecule manipulation 华中科技大学 2022-10-11 CN claimed
CN-114920765-A Aryl boric acid substituted cationic porphyrin array sensor and preparation method and application thereof 南京农业大学 2022-08-19 CN claimed
CN-114505064-A Synthesis method and application of manganese-doped zinc sulfide quantum dots of glucose-6-phosphate 常州磐诺仪器有限公司 2022-05-17 CN claimed
CN-113292880-A High-weather-resistance flame-retardant super-amphiphobic coating capable of being adhered to surface of substrate and construction method thereof 四川大学 2021-08-24 CN claimed
EP-1278551-A2 COMPOSITIONS AND METHODS FOR (IN VIVO) DELIVERY OF POLYNUCLEOTIDE-BASED THERAPEUTICS VICAL INCORPORATED (US) 2003-01-29 EP claimed
US-20020019358-A1 Compositions and methods for in vivo delivery of polynucleotide-based therapeutics VICAL INCORPORATED 2002-02-14 US claimed
WO-2001080897-A2 COMPOSITIONS AND METHODS FOR IN VIVO DELIVERY OF POLYNUCLEOTIDE-BASED THERAPEUTICS VICAL INCORPORATED (US) 2001-11-01 WO claimed
US-12629390-B2 Stabilized amorphous calcium carbonate for treatment of neurological, muscular and infertility diseases or conditions AMORPHICAL LTD. (IL) 2026-05-19 US disclosed
CN-122032323-A Sodium glucose phosphate modified nanofiltration membrane and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-15 CN disclosed
CN-122032323-A Sodium glucose phosphate modified nanofiltration membrane and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-15 CN disclosed
US-4190496-A RECEPTOR, LIGAND, AND ENZYME-BOUND SYVA COMPANY (US) 1980-02-26 US disclosed
US-4156081-A IMMUNOASSAYING SYVA COMPANY (US) 1979-05-22 US disclosed
US-4040907-A CHANGE IN ENZYMATIC ACTIVITY ON BINDING SYVA COMPANY (US) 1977-08-09 US disclosed
US-3931402-A Preparations containing hexoses SOCIETA PRODOTTI ANTIBIOTICI S.P.A. (IT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629390-B2 Stabilized amorphous calcium carbonate for treatment of neurological, muscular and infertility diseases or conditions SMN1; SMN2, CACNA2D1, CACNA2D3 MPI 801/4885PGD 525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.