Mannose 6-Phosphate

Mannose 6-Phosphate

SCHEMBL2387370

O=C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(=O)([O-])[O-].[Na+].[Na+]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Mannose 6-Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.52
PGD P52209 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannose 6-Phosphate SCHEMBL28885847 1.00 MPI (0.52) MPIPGD
Mannose 6-Phosphate SCHEMBL48152 1.00 MPI (0.52) MPIPGD
Mannose 6-Phosphate SCHEMBL21632784 1.00 MPI (0.52) MPIPGD
Mannose 6-Phosphate SCHEMBL9231707 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693684 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693687 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693710 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693713 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL9234969 0.98 MPI (0.50) MPIPGD
Mannose 6-Phosphate SCHEMBL21693697 0.98 MPI (0.50) MPIPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120201991-A Composition for improving skin wrinkles 株式会社LG生活健康 2025-06-24 CN claimed
EP-3946243-B1 ANTI-AGING COSMETIC COMPOSITION GIVAUDAN SA (CH) 2024-06-26 EP claimed
WO-2024106669-A1 COMPOSITION FOR IMPROVING SKIN WRINKLES 주식회사 엘지생활건강 2024-05-23 WO claimed
EP-4272724-A1 SUBSTANCE COMBINATION FOR COSMETIC PREPARATIONS La Prairie Group AG (CH) 2023-11-08 EP claimed
US-20220160607-A1 ANTI-AGING COSMETIC COMPOSITIONS GIVAUDAN SA (CH) 2022-05-26 US claimed
CN-113645947-A Anti-aging cosmetic composition 奇华顿股份有限公司 2021-11-12 CN claimed
US-20250277274-A1 MICROBIOME SIGNATURE GIVAUDAN SA (CH) 2025-09-04 US disclosed
CN-120201991-A Composition for improving skin wrinkles 株式会社LG生活健康 2025-06-24 CN disclosed
CN-119015158-B Cosmetic composition for enhancing mitochondrial energy, application and cosmetic 广东省禾基生物科技有限公司 2025-04-29 CN disclosed
WO-2025044163-A1 ANTI-AGING COMPOSITION FOR REMODELING DERMAL STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF 诺德溯源(广州)生物科技有限公司 2025-03-06 WO disclosed
WO-2025048546-A1 COMPOSITION FOR IMPROVING SKIN CONDITION 주식회사 엘지생활건강 2025-03-06 WO disclosed
CN-119015158-A Cosmetic composition for enhancing mitochondrial energy, application and cosmetic 广东省禾基生物科技有限公司 2024-11-26 CN disclosed
EP-3946243-B1 ANTI-AGING COSMETIC COMPOSITION GIVAUDAN SA (CH) 2024-06-26 EP disclosed
WO-2011117126-A2 SKIN-FRIENDLY ACTIVE INGREDIENT COMBINATION TO COMBAT ACNE BEIERSDORF AG (DE) 2011-09-29 WO disclosed
WO-2011112421-A2 PROBIOTIC COLOR COSMETIC COMPOSITIONS AND METHODS ELC MANAGEMENT LLC (US) 2011-09-15 WO disclosed
US-20110223219-A1 Probiotic Color Cosmetic Compositions And Methods ELC MANAGEMENT LLC 2011-09-15 US disclosed
EP-2364688-A2 Cosmetic preparations with highly elastic texture Beiersdorf AG (DE) 2011-09-14 EP disclosed
EP-2230518-A1 Method for analysis of saccharides JCR Pharmaceuticals CO., LTD. (JP) 2010-09-22 EP disclosed
US-20100233301-A1 TOPICAL COMPOSITIONS COMPRISING FERMENTED EXTRACTS OF TRADITIONAL CHINESE MEDICINAL (TCM) INGREDIENTS, AND METHODS OF MAKING AND USING SAME CHENG JING 2010-09-16 US disclosed
US-20100229634-A1 METHOD FOR ANALYSIS OF SACCHARIDES JCR PHARMACEUTICALS CO., LTD. (JP) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110223219-A1 Probiotic Color Cosmetic Compositions And Methods CUTA, TYR, LPO MPI 3611/4885PGD 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.