SCHEMBL4831944

SCHEMBL4831944

O=C1C2C(C(=O)N1OS(=O)(=O)c1ccc(Cl)cc1)C1C(=O)N(OS(=O)(=O)c3ccc(Cl)cc3)C(=O)C21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 5/20 0.54
HPGD P15428 4/20 0.54
PARL Q9H300 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
KMT2A Q03164 5/20 0.42
MEN1 O00255 3/20 0.42
VDR P11473 2/20 0.42
MAPT P10636 3/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
MMP2 P08253 3/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4837175 0.85 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDPARLTDP1
SCHEMBL4829793 0.84 KMT2A (0.60) ALDH1A1KDM4EHPGDPARLKMT2A
SCHEMBL4827161 0.82 VDR (0.63) ALDH1A1KDM4EHPGDPARLKMT2A
SCHEMBL4834508 0.82 KDM4E (0.54) ALDH1A1KDM4EHPGDPARLKMT2A
SCHEMBL4831794 0.82 PARL (0.43) ALDH1A1KDM4EHPGDPARLKMT2A
SCHEMBL4829803 0.81 PARL (0.65) ALDH1A1KDM4EHPGDPARLTDP1
SCHEMBL1607770 0.80 PARL (0.68) ALDH1A1KDM4EHPGDPARLTDP1
SCHEMBL4835021 0.79 GAA (0.49) PARLTDP1KMT2AMEN1VDR
SCHEMBL4831892 0.78 KMT2A (0.43) ALDH1A1KDM4EHPGDPARLKMT2A
SCHEMBL6650340 0.78 CA1 (0.44) ALDH1A1KDM4EHPGDPARLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 ALDH1A1 633/4885KDM4E 2501/4885HPGD 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.