Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 4/20 | 0.35 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminothiazole SCHEMBL1003511 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TSHRNOS1HSD17B10LMNA | |
| Aminothiazole SCHEMBL4466019 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TSHRNOS1HSD17B10LMNA | |
| Aminothiazole SCHEMBL23647332 | 0.79 | NOS1 (0.75) | ALDH1A1TSHRNOS1HSD17B10MEN1 | |
| Aminothiazole SCHEMBL5907075 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TSHRNOS1HSD17B10LMNA | |
| Aminothiazole SCHEMBL28215372 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TSHRNOS1HSD17B10LMNA | |
| Aminothiazole SCHEMBL28155507 | 0.77 | ALDH1A1 (0.71) | ALDH1A1TSHRNOS1HSD17B10LMNA | |
| Aminothiazole SCHEMBL10585434 | 0.77 | ALDH1A1 (0.71) | ALDH1A1TSHRNOS1HSD17B10LMNA | |
| Aminothiazole SCHEMBL27899272 | 0.77 | — | — | |
| Valine SCHEMBL1389041 | 0.77 | SLC7A5 (0.58) | SLC7A5LMNA | |
| Aminothiazole SCHEMBL1241596 | 0.75 | ALDH1A1 (0.75) | ALDH1A1TSHRNOS1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351727-B2 | Inhibitors of 15-lipoxygenase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-20050065198-A1 | Inhibitors of 15-lipoxygenase | BRISTOL-MYERS SQUIBB COMPANY | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065198-A1 | Inhibitors of 15-lipoxygenase | ALOX15, ALOX5, ALOX15B | ALDH1A1 490/4885TSHR 3036/4885NOS1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.