Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961474 | 0.83 | MAOA (0.56) | MAOAMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL10621855 | 0.74 | HDAC4 (0.47) | MAPTALDH1A1TDP1HSD17B10MAPK1 | |
| SCHEMBL3375220 | 0.74 | CA2 (0.46) | MAPTALDH1A1LMNAIDO1CA1 | |
| SCHEMBL5858478 | 0.74 | MAPT (0.50) | MAOAMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL7222595 | 0.74 | ADORA2A (0.50) | MAOAMAPTALDH1A1TDP1HSD17B10 | |
| SCHEMBL2884290 | 0.74 | CA1 (0.46) | ALDH1A1MAPK1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL9781818 | 0.74 | CES1 (0.38) | MAPTALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7930862 | 0.74 | ALDH1A1 (0.55) | MAPTALDH1A1TDP1ALOX15HSD17B10 | |
| SCHEMBL7584603 | 0.74 | PDCD1 (0.43) | MAOAMAPTALDH1A1HPGDMAOB | |
| SCHEMBL3642843 | 0.72 | PGAM1 (0.40) | MAOAMAPTALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140005370-A1 | MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) | 2014-01-02 | — | — | US | claimed |
| EP-1347463-B1 | Novel electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor | SAMSUNG ELECTRONICS CO LTD (KR) | 2013-05-29 | — | — | EP | claimed |
| US-7341759-B2 | Electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-03-11 | — | — | US | claimed |
| US-6987164-B2 | Electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-01-17 | — | — | US | claimed |
| US-20050208579-A1 | Novel electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor | CHA JUN-HOE | 2005-09-22 | — | — | US | claimed |
| EP-1343494-A4 | TETRAPARTATE PRODRUGS | ENZON INC (US) | 2005-08-03 | — | — | EP | claimed |
| JP-2004518776-A | — | — | 2004-06-24 | — | — | JP | claimed |
| US-20030187182-A1 | Novel electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-10-02 | — | — | US | claimed |
| EP-1347463-A2 | Novel electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor | Samsung Electronics Co., Ltd. (KR) | 2003-09-24 | — | — | EP | claimed |
| EP-1343494-A2 | TETRAPARTATE PRODRUGS | ENZON, INC. (US) | 2003-09-17 | — | — | EP | claimed |
| WO-2002043663-A2 | TETRAPARTATE PRODRUGS | ENZON, INC. (US) | 2002-06-06 | — | — | WO | claimed |
| EP-3463308-B1 | FORMULATIONS OF POLYALKYLENE OXIDE-ASPARAGINASE AND METHODS OF MAKING AND USING THE SAME | SERVIER IP UK LTD (GB) | 2021-12-01 | — | — | EP | disclosed |
| EP-3463308-A2 | FORMULATIONS OF POLYALKYLENE OXIDE-ASPARAGINASE AND METHODS OF MAKING AND USING THE SAME | Servier IP UK Limited (GB) | 2019-04-10 | — | — | EP | disclosed |
| WO-2018017190-A2 | FORMULATIONS OF POLYALKYLENE OXIDE-ASPARAGINASE AND METHODS OF MAKING AND USING THE SAME | BAXALTA INCORPORATED (US) | 2018-01-25 | — | — | WO | disclosed |
| CN-101680039-B | Enzyme anti-cancer treatment | 希格马托罕见疾病有限公司 | 2016-08-24 | — | — | CN | disclosed |
| WO-1999067192-A2 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDE, KETONE, OXIME, AMINE, HYDROXAMIC ACID AND α,β-UNSATURATED CARBOXYLIC ACID AND ALDEHYDE COMPOUNDS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| EP-0946478-A1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999031491-A1 | METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| US-5856560-A | REACTING ACYL CYANIDE BENZENE COMPOUND WITH AN ALCOHOL; THEN AN HYDROXYLAMINE; METHYLATION | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| WO-1998029376-A1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005370-A1 | MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS | GNG2, GDI1, F12 | MAOA 3871/4885MAPT 1554/4885ALDH1A1 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.