Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL486707 | 0.98 | ALOX5 (0.49) | ALOX5MGLLHTR1ADRD2DRD4 | |
| SCHEMBL10424519 | 0.86 | HTR1A (0.59) | ALOX5MGLLHTR1ADRD2DRD4 | |
| SCHEMBL8776692 | 0.82 | NCF1 (0.54) | ALOX5MGLLHTR1ADRD2DRD4 | |
| SCHEMBL6514775 | 0.80 | KEAP1 (0.53) | ALOX5MGLLHTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL29156848 | 0.78 | KEAP1 (0.52) | ALOX5MGLLHTR1ADRD2DRD4 | |
| SCHEMBL1361268 | 0.78 | ADRB1 (0.58) | ALOX5MGLLTSHRLMNAALDH1A1 | |
| SCHEMBL20133784 | 0.78 | HTR1A (0.53) | ALOX5MGLLHTR1ADRD2DRD4 | |
| Nitrogen SCHEMBL4600854 | 0.78 | NCF1 (0.51) | ALOX5MGLLHTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL28740234 | 0.78 | NCF1 (0.56) | ALOX5MGLLHTR1ADRD2DRD4 | |
| Methylamine SCHEMBL6478870 | 0.78 | NCF1 (0.56) | ALOX5MGLLHTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551203-A | Preparation process of fentanyl monoclonal antibody | 浙江工商大学 | 2024-02-13 | — | — | CN | claimed |
| CN-111257574-B | Fluorescent immunity rapid detection card for rapid screening of fentanyl substances and preparation method | 中检国研(北京)科技有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-111257574-A | Fluorescence immunoassay rapid detection card for rapidly screening fentanyl substances and preparation method thereof | 中检国研(北京)科技有限公司 | 2020-06-09 | — | — | CN | claimed |
| US-20060100438-A1 | Process of making fentanyl intermediates | BOEHRINGER INGELHEIM CHEMICALS, INC. (US) | 2006-05-11 | — | — | US | claimed |
| CN-117551203-A | Preparation process of fentanyl monoclonal antibody | 浙江工商大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-111257574-B | Fluorescent immunity rapid detection card for rapid screening of fentanyl substances and preparation method | 中检国研(北京)科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-106795117-B | Heterobicyclic compounds and their use for the treatment of tuberculosis | 大塚制药株式会社 | 2020-06-26 | — | — | CN | disclosed |
| CN-111257574-A | Fluorescence immunoassay rapid detection card for rapidly screening fentanyl substances and preparation method thereof | 中检国研(北京)科技有限公司 | 2020-06-09 | — | — | CN | disclosed |
| US-10464926-B2 | Heterobicyclic compounds and their use for the treatment of tuberculosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-11-05 | — | — | US | disclosed |
| EP-3186240-B1 | HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2019-06-12 | — | — | EP | disclosed |
| US-20180312488-A1 | HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-01 | — | — | US | disclosed |
| US-10053446-B2 | Heterobicyclic compounds and their use for the treatment of tuberculosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-08-21 | — | — | US | disclosed |
| US-4414219-A | ANTICONVULSANTS, TRANQUILIZERS, ANALGESTICS | AMERICAN HOECHST CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4410536-A | 7,8,9,10-Tetrahydrothieno[3,2-e]pyrido[4,3-b]indole compounds and their anti-depressant use | TROPONWERKE GMBH & CO. K.G. (DE) | 1983-10-18 | — | — | US | disclosed |
| EP-0012347-B1 | 7,8,9,10-TETRAHYDROTHIENO(3,2-E)PYRIDO(4,3-B)INDOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Troponwerke GmbH & Co. KG (DE) | 1982-07-28 | — | — | EP | disclosed |
| US-4311703-A | PYRROLIDINE AND PIPERIDINE DERIVATIVES | AMERICAN HOECHST CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4241071-A | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes | AMERICAN HOECHST CORPORATION (US) | 1980-12-23 | — | — | US | disclosed |
| EP-0012347-A1 | 7,8,9,10-Tetrahydrothieno(3,2-e)pyrido(4,3-b)indoles, process for their preparation and medicaments containing them | Troponwerke GmbH & Co. KG (DE) | 1980-06-25 | — | — | EP | disclosed |
| US-3985889-A | 1,3-DIHYDROSPIRO(ISOBENZOFURAN); ANALGETIC AGENTS | AMERICAN HOECHST CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3962259-A | TRANQUILIZERS, ANALGETIC AGENTS | AMERICAN HOECHST CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10053446-B2 | Heterobicyclic compounds and their use for the treatment of tuberculosis | FNTB, SLC11A2, TBCD | ALOX5 3724/4885MGLL 2732/4885HTR1A 4686/4885 |
| US-10464926-B2 | Heterobicyclic compounds and their use for the treatment of tuberculosis | FNTB, SLC11A2, TBCD | ALOX5 3724/4885MGLL 2732/4885HTR1A 4686/4885 |
| US-20180312488-A1 | HETEROBICYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF TUBERCULOSIS | FNTB, SLC11A2, TBCD | ALOX5 3724/4885MGLL 2732/4885HTR1A 4686/4885 |
| US-20060100438-A1 | Process of making fentanyl intermediates | OPRK1, OPRD1, OPRM1 | ALOX5 931/4885MGLL 3923/4885HTR1A 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.