Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486841 | 1.00 | HTR6 (0.52) | HTR6PSIP1CA1CA2ALDH1A1 | |
| SCHEMBL486856 | 1.00 | HTR6 (0.52) | HTR6PSIP1CA1CA2ALDH1A1 | |
| SCHEMBL22116923 | 0.97 | HTR6 (0.50) | HTR6PSIP1CA1CA2ALDH1A1 | |
| Methylphenylsulfone SCHEMBL1332357 | 0.77 | PTGS2 (0.62) | HTR6PSIP1CA1CA2ALDH1A1 | |
| SCHEMBL2285511 | 0.77 | HTR6 (0.58) | HTR6PSIP1CA1CA2ALDH1A1 | |
| Methylphenylsulfone SCHEMBL78253 | 0.77 | PTGS2 (0.62) | HTR6PSIP1CA1CA2ALDH1A1 | |
| SCHEMBL488382 | 0.76 | GAA (0.59) | CA1CA2ALDH1A1TDP1CA12 | |
| (Phenylsulfonyl)Benzene SCHEMBL10870153 | 0.74 | HTR6 (0.82) | HTR6PSIP1CA1CA2ALDH1A1 | |
| Methylphenylsulfone SCHEMBL5499087 | 0.74 | PTGS2 (0.60) | HTR6PSIP1CA1CA2ALDH1A1 | |
| SCHEMBL23145865 | 0.74 | ENPP2 (0.41) | CA1CA2CA12CA3CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | claimed |
| CN-110396114-B | Synthesis method of N-diaryl phosphinyl sulfoxide imine | 成都理工大学 | 2021-08-27 | — | — | CN | claimed |
| EP-0305389-B1 | PROCESS FOR SYNTHESIS OF HOMOCHIRAL FIVE AND SIX RING INTERMEDIATES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-22 | — | — | EP | claimed |
| US-4964846-A | REACTING PROCHIRAL KETONE WITH BUTYLLITHIUM AND SULFOXIMINE, THEN WITH CHLOROTRIMETHYLSILANE | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | claimed |
| US-12503446-B2 | Bromodomain inhibitors | Forschungszentrum Jülich GmbH (DE) | 2025-12-23 | — | — | US | disclosed |
| WO-2025073057-A1 | METHODS FOR PREPARING SULFILIMINES AND SULFOXIMINES FROM THIOETHERS USING O-(DIPHENYLPHOSPHINYL)HYDROXYL AMINE (DPPH), AND AMATOXIN ANALOGS PREPARED FROM SUCH METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2025-04-10 | — | — | WO | disclosed |
| CN-119604487-A | Novel sulfimide derivative or pharmaceutically acceptable salt thereof and application thereof | 韩国科学技术研究院 | 2025-03-11 | — | — | CN | disclosed |
| US-20240308989-A1 | PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | ORION CORP (FI) | 2024-09-19 | — | — | US | disclosed |
| US-12030871-B2 | Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors | ORION CORPORATION (FI) | 2024-07-09 | — | — | US | disclosed |
| EP-4347590-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2024-04-10 | — | — | EP | disclosed |
| WO-2024040267-A2 | DIRECT SYNTHESIS OF N-(3-SUBSTITUTED-CHROMAN-4-YL)-7H- PYRROLO[2,3-D]PYRIMIDIN-4-AMINES AND DERIVATIVES THEREOF | MITOKININ, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| CN-117305865-A | Electrochemical method for preparing N-aroyl sulfoxide imine compound | 桂林理工大学 | 2023-12-29 | — | — | CN | disclosed |
| US-4964846-A | REACTING PROCHIRAL KETONE WITH BUTYLLITHIUM AND SULFOXIMINE, THEN WITH CHLOROTRIMETHYLSILANE | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| EP-0161143-B1 | 1,2,4-THIADIAZINES AND THEIR SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1989-04-12 | — | — | EP | disclosed |
| EP-0305389-A1 | PROCESS FOR SYNTHESIS OF HOMOCHIRAL FIVE AND SIX RING INTERMEDIATES. | SCHERING AG (DE) | 1989-03-08 | — | — | EP | disclosed |
| WO-1987006932-A1 | PROCESS FOR E/Z STEREOSELECTIVE SYNTHESIS OF HOMOCHIRAL FIVE- AND SIX-RING INTERMEDIATES | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-11-19 | — | — | WO | disclosed |
| US-4654338-A | TREATING ANXIETY IN WARM BLOODED ANIMALS | ROUSSEL ULCAF (FR) | 1987-03-31 | — | — | US | disclosed |
| EP-0161143-A1 | 1,2,4-Thiadiazines and their salts, process and intermediates for their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1985-11-13 | — | — | EP | disclosed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | disclosed |
| US-4105795-A | Antispasmodic substituted sulphoximides | LUDWIG HEUMANN & CO. GMBH. (DE) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030871-B2 | Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors | CYP11B1, CYP11B2, CYP4A11 | HTR6 2096/4885PSIP1 2752/4885CA1 2622/4885 |
| US-20240308989-A1 | PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | CYP11B1, CYP11B2, CYP4A11 | HTR6 1947/4885PSIP1 2420/4885CA1 2748/4885 |
| US-12503446-B2 | Bromodomain inhibitors | BRDT, BRD4, BRPF3 | HTR6 3390/4885PSIP1 3259/4885CA1 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.