SCHEMBL487090

SCHEMBL487090

Cc1cc(C)cc(NC(=O)CN(CC(=O)O)CC(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.52
CA1 P00915 10/20 0.51
CA2 P00918 10/20 0.51
TDP1 Q9NUW8 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2097556 0.84 HPGD (0.66) TDP1CYP1A2CYP3A4HDAC3HDAC4
SCHEMBL10640761 0.81 HPGD (0.71) DRD3CA1CA2TDP1CYP3A4
SCHEMBL486592 0.79 POLB (0.65) DRD3CA1CA2TDP1CYP1A2
SCHEMBL27942322 0.77 HDAC3 (0.64) CYP1A2CYP3A4HDAC3HDAC4HDAC1
SCHEMBL9974560 0.77 CA1 (0.64) CA1CA2TDP1HDAC1ALOX15
SCHEMBL9514501 0.76 CA1 (0.68) CA1CA2TDP1ALOX15TSHR
SCHEMBL10640593 0.76 LMNA (0.65) CA1CA2L3MBTL1
SCHEMBL11149052 0.75 KMT2A (0.60) DRD3CA1CA2TDP1KMT2A
SCHEMBL11149049 0.75 ALDH1A1 (0.62) DRD3CA1CA2TDP1KMT2A
SCHEMBL11149123 0.75 CA1 (0.51) DRD3CA1CA2TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
CN-104666246-A Orally Bioavailable Lipid-based Constructs SDG INC AN OHIO CORPRATION 2015-06-03 CN claimed
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal SDG, INC. (US) 2011-06-09 US claimed
WO-2011022396-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2011-02-24 WO claimed
US-7871641-B2 Hepatocyte-targeting vehicle for delivery of glargine insulin to a mammal SDG, INC. (US) 2011-01-18 US claimed
US-7858116-B2 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. (US) 2010-12-28 US claimed
CN-101917971-A Orally bioavailable lipid-based structures SDG INC AN OHIO CORP 2010-12-15 CN claimed
EP-2205217-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (an Ohio Corporation ) (US) 2010-07-14 EP claimed
WO-2009042945-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (AN OHIO CORPORATION ) (US) 2009-04-02 WO claimed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US claimed
EP-1883394-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
WO-2006127361-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal SDG, INC. 2006-10-05 US claimed
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. 2006-10-05 US claimed
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US disclosed
WO-1999059545-A9 TARGETED LIPOSOMAL DRUG DELIVERY SYSTEM SDG INC (US) 2000-04-27 WO disclosed
WO-1999059545-A1 TARGETED LIPOSOMAL DRUG DELIVERY SYSTEM SDG, INC. (US) 1999-11-25 WO disclosed
EP-0274467-B1 HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM GEHO, W., Blair (US) 1992-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 DRD3 2583/4885CA1 2966/4885CA2 2040/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 DRD3 1485/4885CA1 3267/4885CA2 698/4885
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL GPR119, INSR, FABP1 DRD3 1556/4885CA1 3115/4885CA2 2034/4885
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal INSR, GPR119, GCG DRD3 4713/4885CA1 1841/4885CA2 1696/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 DRD3 3168/4885CA1 2202/4885CA2 1569/4885
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal INSR, IAPP, GPR119 DRD3 2882/4885CA1 2697/4885CA2 3633/4885
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal INSR, INSRR, IAPP DRD3 4720/4885CA1 895/4885CA2 1276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.