SCHEMBL4873078

SCHEMBL4873078

O=C1C2=C(C(=O)N1OS(=O)(=O)C(F)(F)F)C1CCC2O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5929449 0.79 PTGS2 (0.33)
SCHEMBL3856715 0.77
SCHEMBL12697178 0.74
SCHEMBL2382893 0.73 VDR (0.33)
SCHEMBL13135726 0.71 PPM1B (0.36)
SCHEMBL3853587 0.69 KDM4E (0.30)
SCHEMBL16883333 0.68 ALDH1A1 (0.34)
SCHEMBL3087267 0.67 PARL (0.50)
SCHEMBL64814 0.67 PARL (0.50)
SCHEMBL4831836 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399577-B2 Halogenated oxime derivatives and the use thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-07-15 US disclosed
US-20060246377-A1 Halogenated oxime derivatives and the use thereof as latent acids BASF SE (DE) 2006-11-02 US disclosed