SCHEMBL4873486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5238328	0.92	THRB (0.44)	SMN1; SMN2ALDH1A1HPGDKDM4EHSD17B10
	SCHEMBL23851296	0.90	MTNR1A (0.52)	ALDH1A1HPGDKDM4EHSD17B10CYP1A2
	SCHEMBL31461239	0.90	MTNR1A (0.52)	ALDH1A1HPGDKDM4EHSD17B10CYP1A2
	SCHEMBL5233120	0.86	TRPV1 (0.44)	MTNR1AMTNR1BTP53TGFBR1
	SCHEMBL3747756	0.83	ALDH1A1 (0.39)	SMN1; SMN2ALDH1A1KDM4ETSHRLMNA
	SCHEMBL24322279	0.83	CDK8 (0.39)	SMN1; SMN2ALDH1A1KDM4EHSD17B10RAB9A
	SCHEMBL31461243	0.83	ALDH1A1 (0.39)	SMN1; SMN2ALDH1A1KDM4ETSHRLMNA
	SCHEMBL29959459	0.82	CYP1A2 (0.49)	SMN1; SMN2ALDH1A1CYP1A2RAB9ATGFBR1
	SCHEMBL5235225	0.82	CYP1A2 (0.49)	SMN1; SMN2ALDH1A1CYP1A2RAB9ATGFBR1
	SCHEMBL5235795	0.82	KDR (0.45)	ALDH1A1CYP1A2MTNR1AMTNR1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.