Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232290 | 0.79 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL29365646 | 0.79 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL31629408 | 0.78 | MAPK1 (0.46) | KDM4EALDH1A1POLBMEN1LMNA | |
| SCHEMBL199221 | 0.78 | TTR (0.54) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL3650453 | 0.78 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRMGAM | |
| Hydrochloric Acid SCHEMBL7476482 | 0.78 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL989115 | 0.78 | KDM4E (0.46) | HCAR2NAPRTMGAMP4HA1P4HTM | |
| SCHEMBL31132753 | 0.77 | ALDH1A1 (0.47) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL476528 | 0.77 | ALDH1A1 (0.47) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL15706875 | 0.76 | HCAR2 (0.47) | HCAR2NAPRTTTRTSHRMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632910-A1 | LACTAM COMPOUND AS FXR RECEPTOR AGONIST | Medshine Discovery Inc. (CN) | 2020-04-08 | — | — | EP | disclosed |
| EP-2049488-B1 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-09 | — | — | EP | disclosed |
| EP-2004636-B1 | Substituted enaminocarbonyl compounds used as insecticides | BAYER IP GMBH (DE) | 2015-04-22 | — | — | EP | disclosed |
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| EP-2707373-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | Bayer Intellectual Property GmbH (DE) | 2014-03-19 | — | — | EP | disclosed |
| EP-2021344-B1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| CN-102105473-B | Tricyclic nitrogen containing compounds and their use as antibacterials | GLAXO GROUP LTD | 2013-05-08 | — | — | CN | disclosed |
| EP-2004606-B1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2012152741-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-11-15 | — | — | WO | disclosed |
| US-8138350-B2 | N′-cyano-N-halogenalkylimidamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8106212-B2 | Substituted enaminocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2012-01-31 | — | — | US | disclosed |
| US-8084452-B2 | Substituted enaminocarbonyl compounds used as insecticides | BAYER CROPSCIENCE AG (DE) | 2011-12-27 | — | — | US | disclosed |
| US-7951951-B2 | Bicyclic enamino(thio)carbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-31 | — | — | US | disclosed |
| US-20100240705-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100048646-A1 | N'-Cyano-N-Halogenalkylimidamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20090247551-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090181947-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247551-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS | DDT, NPEPPS, L3MBTL4 | HCAR2 4590/4885NAPRT 1497/4885TTR 1362/4885 |
| US-20090181947-A1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | TARS2, TBCA, DDT | HCAR2 4477/4885NAPRT 820/4885TTR 143/4885 |
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BROX, BOLA2; BOLA2B, CAT | HCAR2 4183/4885NAPRT 2649/4885TTR 16/4885 |
| US-20100240705-A1 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES | DDT, BCHE, PTMS | HCAR2 4115/4885NAPRT 1003/4885TTR 2363/4885 |
| US-20100048646-A1 | N'-Cyano-N-Halogenalkylimidamide Derivatives | NCLN, NISCH, DDT | HCAR2 4418/4885NAPRT 204/4885TTR 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.