SCHEMBL489304

SCHEMBL489304

CCOC(=O)C(CC(C)C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.43
RNPEP Q9H4A4 1/20 0.43
SLC7A5 Q01650 1/20 0.43
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
CPA1 P15085 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MMP8 P22894 1/20 0.39
GAA P10253 2/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624689 0.98 MME (0.42) MMERNPEPSLC7A5ALDH1A1TDP1
SCHEMBL335607 0.91 ALDH1A1 (0.43) MMEALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL28222034 0.90 RNPEP (0.39) MMERNPEPSLC7A5ALDH1A1TDP1
SCHEMBL10807025 0.88 ALDH1A1 (0.42) MMEALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL30371946 0.88 ALDH1A1 (0.46) ALDH1A1TDP1CYP3A4CYP2C19LMNA
SCHEMBL179900 0.84 ALDH1A1 (0.42) MMEALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL9364109 0.83 TSHR (0.41) MMEALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL27617570 0.83 SOAT1 (0.39) MMEALDH1A1TDP1CYP3A4CYP2C19
SCHEMBL1458577 0.83 MME (0.49) MMEALDH1A1LMNAHSD17B10MMP8
SCHEMBL6895465 0.83 ALOX15 (0.44) MMESLC7A5ALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170104-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) 2025-05-29 US disclosed
US-20250135059-A1 COMPOSITIONS COMPRISING FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY 2025-05-01 US disclosed
EP-4486452-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASSS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2025-01-08 EP disclosed
CN-116813705-A Peptide compound, application thereof and composition containing peptide compound 凯惠科技发展(上海)有限公司 2023-09-29 CN disclosed
WO-2023166039-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-09-07 WO disclosed
WO-2023166039-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-09-07 WO disclosed
CN-109206481-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2023-08-18 CN disclosed
US-20230159546-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2023-05-25 US disclosed
US-20200172575-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2020-06-04 US disclosed
EP-3650464-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND XDCExplorer (Shanghai) Co., Ltd. (CN) 2020-05-13 EP disclosed
WO-1996016027-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-05-30 WO disclosed
EP-0712403-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX INC (US) 1996-05-22 EP disclosed
WO-1995035302-A1 PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY ZAMBON GROUP S.P.A. (IT) 1995-12-28 WO disclosed
WO-1995012603-A1 MATRIX METALLOPROTEASE INHIBITORS________________________________ SYNTEX (U.S.A.) INC. (US) 1995-05-11 WO disclosed
WO-1995004735-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1995-02-16 WO disclosed
EP-0129163-B1 ARPHAMENINE AND ITS RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1987-09-16 EP disclosed
US-4421744-A OPIATE RECEPTOR ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-20 US disclosed
EP-0076557-A2 Peptides and pseudopeptides in which the N terminus bears two substituents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-13 EP disclosed
US-4263293-A ANTIARTHRITIC AGENTS E. R. SQUIBB & SONS, INC. (US) 1981-04-21 US disclosed
US-4005073-A ANTIBIOTICS HOFFMANN-LA ROCHE INC. (US) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159546-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ACE, ACE2, REN MME 439/4885RNPEP 655/4885SLC7A5 2424/4885
US-20250170104-A1 INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß LTA, SERPINB1, LAS1L MME 614/4885RNPEP 537/4885SLC7A5 4416/4885
US-20200172575-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND KISS1R, VIP, NPY1R MME 466/4885RNPEP 311/4885SLC7A5 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.