Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323098 | 0.75 | LMNA (0.36) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL4029872 | 0.75 | FFAR3 (0.36) | HMGCRCHRM1TBXA2RADRA1AFFAR3 | |
| SCHEMBL11416604 | 0.74 | ACLY (0.34) | — | |
| SCHEMBL14163791 | 0.72 | FFAR3 (0.33) | FFAR3 | |
| SCHEMBL14307495 | 0.72 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL16139487 | 0.72 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL9640216 | 0.69 | — | — | |
| SCHEMBL9641013 | 0.69 | — | — | |
| SCHEMBL2177849 | 0.69 | — | — | |
| SCHEMBL11574611 | 0.69 | ACLY (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214870-A1 | Method of Preparing Amine Stereoisomers | HAN ZHENGXU | 2008-09-04 | — | — | US | disclosed |
| US-7332610-B2 | Method of preparing amine stereoisomers | APSINTERM LLC (US) | 2008-02-19 | — | — | US | disclosed |
| US-20060287539-A1 | Method of preparing amine stereoisomers | HAN ZHENGXU | 2006-12-21 | — | — | US | disclosed |
| US-7129378-B2 | Method of preparing amine stereoisomers | APSINTERM, LLC (US) | 2006-10-31 | — | — | US | disclosed |
| US-20050165240-A1 | Method of preparing amine stereoisomers | APSINTERM, LLC | 2005-07-28 | — | — | US | disclosed |
| EP-0513030-B1 | NEW CIS-PLATINUM COMPLEXES WITH CHELATING AMINES AND SULPHINYL CARBOXYLATES | BOEHRINGER MANNHEIM ITALIA (IT) | 1994-01-26 | — | — | EP | disclosed |
| US-5275827-A | Cis-platinum complexes with chelating amines and sulphinyl carboxylates | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165240-A1 | Method of preparing amine stereoisomers | SRM, TST, SMOX | HMGCR 2455/4885CHRM1 543/4885TBXA2R 891/4885 |
| US-20080214870-A1 | Method of Preparing Amine Stereoisomers | SRM, PNMT, SMS | HMGCR 2519/4885CHRM1 474/4885TBXA2R 295/4885 |
| US-20060287539-A1 | Method of preparing amine stereoisomers | SRM, PNMT, SMS | HMGCR 2519/4885CHRM1 474/4885TBXA2R 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.