SCHEMBL491272

SCHEMBL491272

O=S(=O)(CCl)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.61
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HSD11B1 P28845 6/20 0.52
HTR6 P50406 1/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
PLA2G7 Q13093 1/20 0.46
CA9 Q16790 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615420 0.82 CA1 (0.48) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL798585 0.80 PSIP1 (0.56) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL27497483 0.80 CA12 (0.54) ALDH1A1HSD17B10TDP1HSD11B1CA12
SCHEMBL777601 0.78 PSIP1 (0.67) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL64761 0.78 PSIP1 (0.67) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL2914219 0.77 ALDH1A1 (0.56) ALDH1A1HSD11B1CA12CA1CA2
SCHEMBL3394881 0.77 PSIP1 (0.52) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL3329009 0.76 PSIP1 (0.64) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL180713 0.76 PSIP1 (1.00) PSIP1ALDH1A1HSD17B10TDP1HSD11B1
SCHEMBL11666329 0.75 CA2 (0.57) ALDH1A1HSD17B10CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN claimed
CN-118756494-A Flame-retardant finishing agent for textile and application thereof 苏州棠华纳米科技有限公司 2024-10-11 CN claimed
CN-106866507-B A kind of synthetic method for tieing up not Buddhist nun 武汉博诚恒瑞医药科技有限公司 2019-08-02 CN claimed
CN-106892863-B The preparation method of vismodegib and its intermediate 山东大学 2019-06-11 CN claimed
CN-105017101-B Synthesizing method of 2-chloro-4-(methylsulfonyl)benzoic acid 浙江大学 2017-03-22 CN claimed
CN-100335486-C Preparation method of [(phenyl sulfonyl) difluoro methyl] trimethyl silane SHANGHAI INST ORGANIC CHEM (CN) 2007-09-05 CN claimed
CN-1923781-A Method of synthesizing compound containing difluoromethyl group SHANGHAI INST ORGANIC CHEM (CN) 2007-03-07 CN claimed
EP-1256608-B1 Inkjet inks HEWLETT PACKARD CO (US) 2005-11-30 EP claimed
WO-2004106324-A1 AZOLECARBOXAMIDE HERBICIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-12-09 WO claimed
EP-1256608-A2 Inkjet inks Hewlett-Packard Company (US) 2002-11-13 EP claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-12559480-B2 Methods of treatment using phenyl indole allosteric inhibitors of P97 ATPase University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2026-02-24 US disclosed
WO-2024261237-A1 FLUOROMETHYL-CARNITINE FOR USE AS A CHOLINE TRIMETHYLAMINE (TMA) LYASE INHIBITOR ALFASIGMA S.P.A. (IT) 2024-12-26 WO disclosed
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN disclosed
EP-4337008-A1 AGROCHEMICAL COMPOSITION, AGROCHEMICAL FORMULATION, USE OF A DIOXABICYCLOALKANE DERIVATIVE, AND, METHOD FOR THE TREATMENT AND/OR PREVENTION OF DISEASES OR PESTS IN A PLANT OR PLANT SEED Oxiteno S.A. Indústria e Comércio (BR) 2024-03-20 EP disclosed
EP-0160996-B1 HEAT DEVELOPABLE LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-11-23 EP disclosed
US-4705737-A Heat developable photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1987-11-10 US disclosed
US-4420433-A REACTION WITH SILICON TETRACHLORIDE OR TITANIUM TETRACHLORIDE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-13 US disclosed
US-3988375-A HERBICIDES MONSANTO COMPANY (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559480-B2 Methods of treatment using phenyl indole allosteric inhibitors of P97 ATPase TMEM97, ADRM1, ABCB11 PSIP1 4056/4885ALDH1A1 2497/4885HSD17B10 2088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.