Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928804 | 0.88 | MAPK1 (0.43) | TP53SMN1; SMN2HSD11B1LMNAALDH1A1 | |
| SCHEMBL4917411 | 0.79 | STAT3 (0.53) | TP53SMN1; SMN2LMNAALDH1A1USP2 | |
| SCHEMBL7386917 | 0.74 | TP53 (0.57) | TP53SMN1; SMN2LMNAALDH1A1USP2 | |
| SCHEMBL4927290 | 0.71 | SIRT2 (0.48) | TP53SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL2943913 | 0.69 | LMNA (0.50) | SMN1; SMN2LMNA | |
| SCHEMBL1858294 | 0.68 | KMT2A (0.47) | TP53SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL246278 | 0.67 | CA1 (0.42) | TP53SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9478142 | 0.67 | TP53 (0.73) | TP53LMNAALDH1A1USP2MAPT | |
| SCHEMBL8946077 | 0.67 | ELANE (0.46) | TP53SMN1; SMN2ALDH1A1MAPTF2 | |
| SCHEMBL7314095 | 0.67 | MMP1 (0.48) | TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188659-A1 | Method for Preparing Halogenated Amines | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080188659-A1 | Method for Preparing Halogenated Amines | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080188659-A1 | Method for Preparing Halogenated Amines | WYETH (US) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188659-A1 | Method for Preparing Halogenated Amines | PNMT, ABL1, INMT | TP53 3224/4885SMN1; SMN2 3833/4885HSD11B1 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.