Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.62 |
| ▸ | GABRP | O00591 | 4/20 | 0.56 |
| ▸ | GABRD | O14764 | 4/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251765 | 0.86 | GABRP (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8230790 | 0.85 | GABRP (0.54) | HDAC6HDAC1GABRPGABRDGABRA1 | |
| SCHEMBL31411210 | 0.81 | GPR84 (0.67) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL445121 | 0.81 | MAPT (0.61) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL4916893 | 0.78 | HDAC1 (0.68) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL6205660 | 0.77 | ADORA2A (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5804384 | 0.77 | IGF1R (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2829167 | 0.77 | HDAC6 (1.00) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7742074 | 0.76 | NHERF1 (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17831086 | 0.76 | GABRP (0.68) | HDAC6HDAC1HDAC2HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2008-10-30 | — | — | US | disclosed |
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | disclosed |
| EP-1796681-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | Genmedica Therapeutics SL (ES) | 2007-06-20 | — | — | EP | disclosed |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | disclosed |
| WO-2006013209-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | GENMEDICA THERAPEUTICS SL (ES) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | HDAC6 2092/4885HDAC1 563/4885HDAC2 2145/4885 |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | HDAC6 2060/4885HDAC1 622/4885HDAC2 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.