SCHEMBL4925825

SCHEMBL4925825

CC(NC(=O)c1ccc(N)c(O)c1)c1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
MMP9 P14780 1/20 0.53
HPGDS O60760 2/20 0.52
ROCK2 O75116 1/20 0.51
ROCK1 Q13464 1/20 0.51
DRD2 P14416 1/20 0.49
DRD3 P35462 1/20 0.49
PDE2A O00408 2/20 0.49
F7 P08709 2/20 0.46
F2 P00734 1/20 0.46
F10 P00742 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1320071 0.84 MMP9 (0.58) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL12121924 0.81 MMP9 (0.64) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL1318145 0.80 HPGDS (0.60) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL1643774 0.78 TP53 (0.55) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL1320867 0.78 MEN1 (0.59) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL23839968 0.78 MEN1 (0.59) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL1320543 0.78 MEN1 (0.64) MEN1KMT2AMMP9HPGDSROCK2
SCHEMBL1321337 0.78 ALDH1A1 (0.68) MEN1KMT2AMMP9HPGDSPDE2A
SCHEMBL4925844 0.78 ALOX5 (0.60) MEN1KMT2AMMP9HPGDSPDE2A
SCHEMBL29375958 0.77 MMP9 (0.56) MEN1KMT2AMMP9HPGDSROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US claimed
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 MEN1 1562/4885KMT2A 3374/4885MMP9 856/4885
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 MEN1 1683/4885KMT2A 3243/4885MMP9 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.