SCHEMBL4926951

SCHEMBL4926951

CCCc1ccc(S(=O)(=O)N(O)C(C(N)=O)C(C)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.45
CNR2 P34972 2/20 0.43
CA1 P00915 6/20 0.40
CA12 O43570 4/20 0.40
CA9 Q16790 4/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
PSMB5 P28074 1/20 0.38
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4916977 0.82 ALDH1A1 (0.41) CA2CNR2CA1CA12CA9
SCHEMBL4925174 0.80 CA2 (0.46) CA2CNR2CA1CA12CA9
SCHEMBL4926929 0.74 NPC1 (0.45) LMNAHTR2C
SCHEMBL7987856 0.69 MMP9 (0.49) CA2CA1CA9ALDH1A1GAA
SCHEMBL4928565 0.69 MMP2 (0.45) ALDH1A1LMNASMN1; SMN2
SCHEMBL8337020 0.68 CA2 (0.60) CA2CNR2ALDH1A1LMNAHTR2A
SCHEMBL11889489 0.67 CA2 (0.69) CA2CNR2ALDH1A1LMNAHTR2A
Valine SCHEMBL8429982 0.66 CA2 (0.49) CA2CA1ALDH1A1LMNAGAA
SCHEMBL6793165 0.66 CA2 (0.67) CA2CNR2ALDH1A1LMNAHTR2A
SCHEMBL6618290 0.65 CA2 (0.59) CA2CNR2ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US claimed
JP-2008508348-A 2008-03-21 JP claimed
EP-1796681-A2 COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF Genmedica Therapeutics SL (ES) 2007-06-20 EP claimed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US claimed
WO-2006013209-A2 COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF GENMEDICA THERAPEUTICS SL (ES) 2006-02-09 WO claimed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 CA2 3279/4885CNR2 4335/4885CA1 2819/4885
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 CA2 3365/4885CNR2 4342/4885CA1 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.