Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932130 | 0.80 | ADRA2C (0.35) | MARS1ADRA2CCYP3A4CYP2C9CRHR1 | |
| SCHEMBL1072714 | 0.79 | LMNA (0.35) | MARS1ADRA2CCYP3A4CYP2C9CRHR1 | |
| SCHEMBL9716496 | 0.68 | MARS1 (0.47) | MARS1CRHR1 | |
| SCHEMBL4932128 | 0.65 | IDO1 (0.40) | CYP3A4CYP2C9CRHR1IDO1TSHR | |
| SCHEMBL10308906 | 0.63 | ATM (0.32) | MEN1KMT2A | |
| SCHEMBL4932106 | 0.63 | CRHR1 (0.36) | MARS1CYP3A4CRHR1TP53MAPT | |
| SCHEMBL3192743 | 0.61 | ADRA2C (0.50) | ADRA2CIDO1TP53TSHRNPSR1 | |
| SCHEMBL31074209 | 0.61 | ADRA2C (0.50) | ADRA2CIDO1TP53TSHRNPSR1 | |
| SCHEMBL14109383 | 0.59 | MAOB (0.35) | — | |
| SCHEMBL17513258 | 0.59 | TP53 (0.53) | ADRA2CCYP3A4IDO1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188129-B2 | (−)-enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | BAYER AKTIENGESELLSCHAFT (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20080113864-A1 | (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
| US-6455472-B1 | HERBICIDES, ACARICIDES, NEMATICIDES AND INSECTICIDES FOR CROPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113864-A1 | (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | CYP51A1, CTRL, CASP2 | MARS1 1911/4885ADRA2C 1183/4885CYP3A4 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.