Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888003 | 0.72 | IDO1 (0.69) | IDO1MRGPRX4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9716496 | 0.70 | MARS1 (0.47) | KCNH2CRHR1 | |
| SCHEMBL10636887 | 0.70 | IDO1 (0.56) | IDO1MRGPRX4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5106102 | 0.70 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL4932130 | 0.66 | ADRA2C (0.35) | IDO1KMT2ACYP3A4HTTCYP2C9 | |
| SCHEMBL4932106 | 0.65 | CRHR1 (0.36) | KMT2ASMN1; SMN2CYP3A4MAPK1TSHR | |
| SCHEMBL4932111 | 0.65 | MARS1 (0.35) | IDO1KMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL1072714 | 0.65 | LMNA (0.35) | KMT2AMEN1CYP3A4HTTCYP2C9 | |
| SCHEMBL28649281 | 0.65 | IDO1 (0.62) | IDO1MRGPRX4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9367249 | 0.64 | IDO1 (0.49) | IDO1MRGPRX4KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188129-B2 | (−)-enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | BAYER AKTIENGESELLSCHAFT (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20080113864-A1 | (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
| US-6455472-B1 | HERBICIDES, ACARICIDES, NEMATICIDES AND INSECTICIDES FOR CROPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113864-A1 | (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | CYP51A1, CTRL, CASP2 | IDO1 56/4885MRGPRX4 2585/4885KMT2A 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.