Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932111 | 0.80 | MARS1 (0.35) | ADRA2CCRHR1CYP3A4CYP2C9MARS1 | |
| SCHEMBL1072714 | 0.80 | LMNA (0.35) | ADRA2CCRHR1CYP3A4CYP2C9MARS1 | |
| SCHEMBL9716496 | 0.69 | MARS1 (0.47) | CRHR1MARS1KCNH2SPR | |
| SCHEMBL10308906 | 0.67 | ATM (0.32) | KCNH2KMT2A | |
| SCHEMBL4932128 | 0.66 | IDO1 (0.40) | CRHR1CYP3A4CYP2C9IDO1LMNA | |
| SCHEMBL10692817 | 0.66 | KMT2A (0.38) | CYP2C9IDO1TDO2KMT2A | |
| SCHEMBL4932106 | 0.64 | CRHR1 (0.36) | CRHR1CYP3A4MARS1TP53KMT2A | |
| SCHEMBL5106102 | 0.64 | KMT2A (0.37) | CRHR1CYP3A4CYP2C9MARS1LMNA | |
| SCHEMBL6203042 | 0.62 | TP53 (0.52) | ADRA2CIDO1TDO2LMNATP53 | |
| SCHEMBL8632275 | 0.62 | LMNA (0.38) | TRPC5IDO1TDO2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188129-B2 | (−)-enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | BAYER AKTIENGESELLSCHAFT (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20080113864-A1 | (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
| US-6455472-B1 | HERBICIDES, ACARICIDES, NEMATICIDES AND INSECTICIDES FOR CROPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113864-A1 | (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione | CYP51A1, CTRL, CASP2 | ADRA2C 1183/4885CRHR1 3766/4885CYP3A4 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.