Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932106 | 0.77 | CRHR1 (0.36) | KMT2AL3MBTL1NPC1TDP1SMN1; SMN2 | |
| SCHEMBL4932128 | 0.70 | IDO1 (0.40) | KMT2AL3MBTL1MEN1TDP1NR3C1 | |
| SCHEMBL9716496 | 0.68 | MARS1 (0.47) | NPC1CRHR1MARS1 | |
| SCHEMBL1072714 | 0.67 | LMNA (0.35) | KMT2AMEN1HTTCRHR1CYP3A4 | |
| SCHEMBL3030151 | 0.64 | GGPS1 (0.56) | KMT2AGGPS1NPC1MEN1NR3C1 | |
| SCHEMBL6886022 | 0.64 | GGPS1 (0.55) | KMT2AGGPS1MEN1TDP1NR3C1 | |
| SCHEMBL4932130 | 0.64 | ADRA2C (0.35) | KMT2AHTTCRHR1CYP3A4CYP2C9 | |
| SCHEMBL29018294 | 0.63 | GGPS1 (0.50) | GGPS1L3MBTL1TDP1NR3C1PGR | |
| SCHEMBL4932111 | 0.63 | MARS1 (0.35) | KMT2AMEN1CRHR1CYP3A4CYP2C9 | |
| SCHEMBL12961098 | 0.62 | GGPS1 (0.50) | KMT2AGGPS1NPC1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345080-B2 | Substituted 4-pyrazolyl pyrazonlines used for pest control | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20050159603-A1 | Substituted 4-pyrazolyl pyrazonlines used for pest control | BAYER CROPSCIENCE AG (DE) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159603-A1 | Substituted 4-pyrazolyl pyrazonlines used for pest control | L3MBTL4, L3MBTL3, PTMS | KMT2A 2010/4885GGPS1 1596/4885L3MBTL1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.