SCHEMBL493910

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10064396	0.76	ALDH1A1 (0.35)	ALDH1A1KDM4EHPGDLMNAL3MBTL1
	SCHEMBL9927433	0.75	FKBP1A (0.34)	CA1CA9ALDH1A1KDM4EKMT2A
	SCHEMBL74568	0.73	ALDH1A1 (0.38)	ALDH1A1KDM4EHPGDLMNA
	SCHEMBL75437	0.71	CA1 (0.38)	CA1CA9ALDH1A1KDM4EKMT2A
	SCHEMBL674286	0.71	ALDH1A1 (0.39)	ALDH1A1
	SCHEMBL24908878	0.71	FKBP1A (0.35)	ALDH1A1KDM4EHPGDLMNA
	SCHEMBL10936325	0.70	ALDH1A1 (0.41)	ALDH1A1
	SCHEMBL21420098	0.70	MAPK1 (0.35)	CA1KDM4EHSD17B10KMT2AATM
	SCHEMBL9436287	0.69	CA1 (0.39)	CA1CA9
	SCHEMBL9927430	0.69	CA1 (0.46)	CA1CA9ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.