Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.70 |
| ▸ | CA1 known ✓ | P00915 | 16/20 | 0.45 |
| ▸ | CA2 known ✓ | P00918 | 16/20 | 0.45 |
| ▸ | CA4 known ✓ | P22748 | 6/20 | 0.45 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | EYA2 | O00167 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL2406173 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL6347089 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL887881 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL5697081 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL6347093 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL121983 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL7870390 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL59899 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL5305791 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E | |
| Edetic Acid SCHEMBL64648 | 1.00 | TDP1 (0.70) | TDP1EYA2APPACEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 80360 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691647-B1 | NEW TREATMENT OF SMA | HOFFMANN LA ROCHE (CH) | 2026-05-27 | — | — | EP | claimed |
| CN-121197003-B | Preparation method and application of composition for repairing sensitive muscles | Best Beauty Biotechnology (Zhejiang) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121533943-B | Relief and repair composition and application thereof in cosmetics | GUANGZHOU DANKE NETWORK TECHNOLOGY Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121732176-B | Efficient desulfurizing agent, preparation method and application thereof in heavy naphtha desulfurization | HUBEI HUABANG CHEMICAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122081014-A | Silver-based micro-nano structure protective quick-drying cleaning agent and preparation and use methods thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081071-A | Compound microorganism freeze-drying protective agent and preparation method and application method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075349-A | Formula and preparation process of efficient and stable natural sulfur hot spring bath concentrate | — | 2026-05-26 | — | — | CN | claimed |
| CN-122082066-A | Household appliance accessory surface treatment process | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075424-A | Bisoprolol fumarate tablet with long-term storage stability and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084348-A | Neutral dissociating agent for detecting 25-hydroxy vitamin D content in human blood sample and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-4227882-A | DISCOLORATION INHIBITION BY TREATMENT WITH AN AMINOALKYLCARBOXY ACID OR SALT | KANEBO, LTD. (JP) | 1980-10-14 | — | — | US | claimed |
| EP-0011868-A1 | Methyldopa composition | MERCK & CO. INC. (US) | 1980-06-11 | — | — | EP | claimed |
| US-4199602-A | Control of mastitis and compositions therefor | ECONOMICS LABORATORY, INC. (US) | 1980-04-22 | — | — | US | claimed |
| US-4120949-A | POLYVINYL ALCOHOL, HYDROXYETHYL CELLULSOE, POLYVINYLPYRROLIDONE, AND HYDROXYPROPYL METHYLCELLULOSE, TREATMENT OF DRY EYE SYNDROME | COOPER LABORATORIES, INC. (US) | 1978-10-17 | — | — | US | claimed |
| US-4073907-A | CARBON DIOXIDE-FREE, SODIUM EDETATE, CRYSTAL GROWTH INHIBITION | ABBOTT LABORATORIES (US) | 1978-02-14 | — | — | US | claimed |
| US-4046706-A | ETHYLENE OXIDE-PROPYLENE OXIDE BLOCK COPOLYMER | FLOW PHARMACEUTICALS, INC. (US) | 1977-09-06 | — | — | US | claimed |
| US-4039682-A | METHOD AND COMPOSITION FOR RELIEF OF BACK PAIN | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1977-08-02 | — | — | US | claimed |
| US-4000016-A | Water soluble fluxes | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1976-12-28 | — | — | US | claimed |
| US-3997348-A | FERRIC SALT BLEACHING SOLUTION | FUJI PHOTO FILM CO., LTD. (JA) | 1976-12-14 | — | — | US | claimed |
| US-3954644-A | ETHYLENE OXIDE-PROPYLENE OXIDE BLOCK COPOLYMER | FLOW PHARMACEUTICALS, INC. (US) | 1976-05-04 | — | — | US | claimed |