Edetic Acid

Edetic Acid

SCHEMBL64648

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE known ✓ P12821 1/20 0.70
CA1 known ✓ P00915 16/20 0.45
CA2 known ✓ P00918 16/20 0.45
CA4 known ✓ P22748 6/20 0.45
CA12 known ✓ O43570 3/20 0.38
TDP1 Q9NUW8 2/20 0.70
EYA2 O00167 1/20 0.70
APP P05067 1/20 0.70
KDM4E B2RXH2 2/20 0.67
ALOX15 P16050 2/20 0.67
BLM P54132 2/20 0.67
PMP22 Q01453 2/20 0.67
LMNA P02545 1/20 0.67
CHRM2 P08172 1/20 0.67
ADRA2A P08913 1/20 0.67
TSHR P16473 1/20 0.67
DRD1 P21728 1/20 0.67
SLC6A2 P23975 1/20 0.67
SLC6A4 P31645 1/20 0.67
CYP2C19 P33261 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL2406173 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL6347089 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL49459 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL887881 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL5697081 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL6347093 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL121983 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL7870390 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL59899 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E
Edetic Acid SCHEMBL5305791 1.00 TDP1 (0.70) TDP1EYA2APPACEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160230127-A1 Low-VOC Water-Based Cleaner For Pen, Ink, Markers, Paint STONER, INC. 2016-08-11 US claimed
US-20160222326-A1 Low VOC Composition To Remove Food, Beverage, Pet and Protein Stains STONER, INC. 2016-08-04 US claimed
WO-2015134011-A1 LOW-VOC WATER-BASED CLEANER FOR PEN, INK, MARKERS, PAINT MOTSENBOCKER GREGG A (US) 2015-09-11 WO claimed
WO-2015133995-A1 LOW VOC COMPOSITION TO REMOVE FOOD, BEVERAGE, PET AND PROTEIN STAINS MOTSENBOCKER GREGG A (US) 2015-09-11 WO claimed
US-20110190441-A1 NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2011-08-04 US claimed
EP-2349436-A2 DEVICE FOR DELIVERY OF ANTIMICROBIAL AGENT INTO TRANS-DERMAL CATHETER Pursuit Vascular, Inc. (US) 2011-08-03 EP claimed
US-12102632-B2 Quinolone dispersions SOMERSET THERAPEUTICS, LLC (US) 2024-10-01 US disclosed
US-12016855-B2 Prednisolone and moxifloxacin compositions and methods SOMERSET THERAPEUTICS, LLC (US) 2024-06-25 US disclosed
CN-114286849-B Adhesive composition 罗门哈斯公司 2024-02-27 CN disclosed
US-20240043479-A1 MALASSEZIA FACTOR WITH ANTIBIOTIC ACTIVITY UNIVERSITY OF OREGON (US) 2024-02-08 US disclosed
US-11845998-B2 Phosphorus acid functionalized coating composition ROHM AND HAAS COMPANY (US) 2023-12-19 US disclosed
WO-2023234926-A1 PEST CONTROL COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-12-07 WO disclosed
US-11820799-B2 Malassezia factor with antibiotic activity UNIVERSITY OF OREGON (US) 2023-11-21 US disclosed
EP-0554585-A1 A method for making a lithographic printing plate according to the silver salt diffusion transfer process AGFA-GEVAERT N.V. (BE) 1993-08-11 EP disclosed
EP-0547660-A1 A method for making a lithographic printing plate according to the silver salt diffusion transfer process AGFA-GEVAERT N.V. (BE) 1993-06-23 EP disclosed
EP-0386733-A1 cDNA coding for placenta protein 9 (PP9), its isolation and its use BEHRINGWERKE Aktiengesellschaft (DE) 1990-09-12 EP disclosed
EP-0374909-A2 CDNA coding for placental protein 11 (PP11), its isolation and use BEHRINGWERKE Aktiengesellschaft (DE) 1990-06-27 EP disclosed
EP-0333134-A2 Gentechnological preparation of protein PP 15. BEHRINGWERKE Aktiengesellschaft (DE) 1989-09-20 EP disclosed
EP-0315081-A2 Anti-coagulating protein PP4-x, its preparation and use BEHRINGWERKE Aktiengesellschaft (DE) 1989-05-10 EP disclosed
EP-0236978-A2 Production of factor XIIIa by gene technology BEHRINGWERKE Aktiengesellschaft (DE) 1987-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12102632-B2 Quinolone dispersions F12, CFD, NFKBIA ACE 2017/4885CA1 3524/4885CA2 610/4885
US-12016855-B2 Prednisolone and moxifloxacin compositions and methods SERPINA6, PF4, F12 ACE 1874/4885CA1 3761/4885CA2 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.