Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | METAP1 | P53582 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949292 | 0.92 | NAAA (0.51) | METAP2METAP1ACENAAACASP1 | |
| SCHEMBL4956720 | 0.89 | ACE (0.49) | ACENAAACASP1CASP3CASP7 | |
| SCHEMBL4949621 | 0.88 | MME (0.49) | METAP2METAP1NAAACASP1CASP3 | |
| SCHEMBL4957034 | 0.84 | KEAP1 (0.49) | ACENAAACASP1CASP3CASP7 | |
| SCHEMBL3901340 | 0.81 | MME (0.63) | ACENAAAMMEKEAP1NFE2L2 | |
| SCHEMBL3898655 | 0.81 | MME (0.63) | ACENAAAMMEKEAP1NFE2L2 | |
| SCHEMBL3913656 | 0.81 | MME (0.63) | ACENAAAMMEKEAP1NFE2L2 | |
| SCHEMBL3898657 | 0.81 | MME (0.63) | ACENAAAMMEKEAP1NFE2L2 | |
| SCHEMBL3906073 | 0.81 | MME (0.63) | ACENAAAMMEKEAP1NFE2L2 | |
| SCHEMBL4957031 | 0.81 | METAP2 (0.48) | METAP2METAP1NAAACASP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465471-B2 | Palatability of aquaculture feed | NOVUS INTERNATIONAL, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| WO-2007147155-A1 | POLYOL ESTER COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070292485-A1 | POLYOL ESTER COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2007-12-20 | — | — | US | disclosed |
| US-20050215623-A1 | Palatability of aquaculture feed | NOVUS INTERNATIONAL, INC. (US) | 2005-09-29 | — | — | US | disclosed |
| US-20040175434-A1 | Antimicrobial compositions | NOVUS INTERNATIONAL, INC. | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292485-A1 | POLYOL ESTER COMPOUNDS | PNLIP, ELOVL1, ELOVL5 | METAP2 2666/4885METAP1 3714/4885ACE 837/4885 |
| US-20050215623-A1 | Palatability of aquaculture feed | TAS2R3, TAS2R1, TAS2R20 | METAP2 3008/4885METAP1 2414/4885ACE 518/4885 |
| US-20040175434-A1 | Antimicrobial compositions | MRPL21, FPR1, ARG1 | METAP2 3176/4885METAP1 1638/4885ACE 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.