SCHEMBL4955830

SCHEMBL4955830

CSCCC(NCCCC(C)C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.43
LMNA P02545 2/20 0.41
RNPEP Q9H4A4 1/20 0.41
FNTA P49354 3/20 0.40
FNTB P49356 3/20 0.40
PGGT1B P53609 1/20 0.40
BLM P54132 1/20 0.40
ALDH1A1 P00352 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GGT1 P19440 1/20 0.38
PKM P14618 1/20 0.38
GAA P10253 1/20 0.38
POLB P06746 1/20 0.38
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4955299 0.87 FOLH1 (0.42) FOLH1LMNABLMGGT1
SCHEMBL4956707 0.84 BLM (0.38) FOLH1BLMGGT1
SCHEMBL27750256 0.83 NOD1 (0.47) FOLH1LMNARNPEPFNTAFNTB
SCHEMBL17004002 0.83 LMNA (0.43) FOLH1LMNARNPEPFNTAFNTB
SCHEMBL29428966 0.83 NOD1 (0.47) FOLH1LMNARNPEPFNTAFNTB
SCHEMBL4953816 0.83 ACE2 (0.38) FOLH1BLMGGT1
SCHEMBL8755755 0.83 RNPEP (0.48) FOLH1LMNARNPEPFNTAFNTB
SCHEMBL149342 0.83 RNPEP (0.48) FOLH1LMNARNPEPFNTAFNTB
SCHEMBL303333 0.82 NOD1 (0.49) FOLH1LMNARNPEPFNTAFNTB
SCHEMBL7385079 0.82 FOLH1 (0.47) FOLH1LMNARNPEPFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465471-B2 Palatability of aquaculture feed NOVUS INTERNATIONAL, INC. (US) 2008-12-16 US disclosed
WO-2007147155-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-21 WO disclosed
US-20070292485-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-20 US disclosed
US-20050215623-A1 Palatability of aquaculture feed NOVUS INTERNATIONAL, INC. (US) 2005-09-29 US disclosed
EP-1531672-A2 ANTIMICROBIAL COMPOSITIONS Novus International, Inc. (US) 2005-05-25 EP disclosed
US-20040175434-A1 Antimicrobial compositions NOVUS INTERNATIONAL, INC. 2004-09-09 US disclosed
WO-2004019683-A2 ANTIMICROBIAL COMPOSITIONS NOVUS INTERNATIONAL, INC. (US) 2004-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292485-A1 POLYOL ESTER COMPOUNDS PNLIP, ELOVL1, ELOVL5 FOLH1 1682/4885LMNA 1572/4885RNPEP 3086/4885
US-20050215623-A1 Palatability of aquaculture feed TAS2R3, TAS2R1, TAS2R20 FOLH1 2075/4885LMNA 4474/4885RNPEP 1217/4885
US-20040175434-A1 Antimicrobial compositions MRPL21, FPR1, ARG1 FOLH1 4314/4885LMNA 2272/4885RNPEP 2140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.