SCHEMBL4960653

SCHEMBL4960653

Oc1cc(Oc2ccccc2)cc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 2/20 0.52
▸ NR1H2 P55055 1/20 0.52
▸ BAX Q07812 1/20 0.52
▸ BACE1 P56817 1/20 0.52
▸ TTR P02766 2/20 0.47
▸ TSHR P16473 1/20 0.46
▸ THRA P10827 1/20 0.43
▸ THRB P10828 1/20 0.43
▸ CAMK2A Q9UQM7 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ TUBB4A P04350 1/20 0.42
▸ TUBB P07437 1/20 0.42
▸ TUBA3C P0DPH7 1/20 0.42
▸ TUBA1B P68363 1/20 0.42
▸ TUBA4A P68366 1/20 0.42
▸ TUBB4B P68371 1/20 0.42
▸ TUBB3 Q13509 1/20 0.42
▸ TUBB2A Q13885 1/20 0.42
▸ TUBB8 Q3ZCM7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093898 0.79 LTA4H (0.55) LTA4HNR1H2BAXTTRTSHR
SCHEMBL8720658 0.77 TTR (0.44) LTA4HNR1H2BAXBACE1TTR
SCHEMBL11018352 0.76 LTA4H (0.51) LTA4HTTRCAMK2AKDM4EHSD17B10
SCHEMBL2094795 0.76 LTA4H (0.50) LTA4HNR1H2BAXTTRTSHR
SCHEMBL4958922 0.76 TTR (0.65) LTA4HNR1H2BAXTTRTSHR
SCHEMBL982183 0.76 ALDH1A1 (0.47) LTA4HNR1H2BAXTTRTSHR
SCHEMBL5380053 0.76 THRA (0.56) LTA4HNR1H2BAXTTRTSHR
SCHEMBL5991731 0.76 THRA (0.56) LTA4HNR1H2BAXTTRTSHR
SCHEMBL2094797 0.76 LTA4H (0.56) LTA4HTTRTSHRKDM4EHSD17B10
SCHEMBL5712250 0.74 LTA4H (0.65) LTA4HNR1H2BAXTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 — — WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 — — EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 — — EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 — — WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 — — US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 — — US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 — — US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 — — US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR LTA4H 2285/4885NR1H2 2546/4885BAX 1152/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT LTA4H 2769/4885NR1H2 4848/4885BAX 1186/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 LTA4H 974/4885NR1H2 2488/4885BAX 2620/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 LTA4H 1153/4885NR1H2 4694/4885BAX 2420/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH LTA4H 457/4885NR1H2 2961/4885BAX 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback