SCHEMBL4966748

SCHEMBL4966748

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nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.58
GSTK1 Q9Y2Q3 1/20 0.58
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
PTGS2 P35354 2/20 0.50
LMNA P02545 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ACE P12821 5/20 0.46
MME P08473 5/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
ECE1 P42892 2/20 0.41
GLO1 Q04760 1/20 0.39
BLM P54132 2/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
NPEPPS P55786 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4966736 1.00 PTGS1 (0.58) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL29379914 0.90 PTGS1 (0.50) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL31391105 0.87 PTGS1 (0.50) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL29351498 0.85 ALDH1A1 (0.47) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL29637953 0.85 PTGS1 (0.64) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL24130552 0.85 ALDH1A1 (0.47) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL29410682 0.85 ALDH1A1 (0.47) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL17283446 0.85 ALDH1A1 (0.47) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL3495921 0.83 ALDH1A1 (0.46) PTGS1GSTK1ALDH1A1MAPTPTGS2
SCHEMBL6657992 0.83 ALDH1A1 (0.46) PTGS1GSTK1ALDH1A1MAPTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655007-A1 ANTIBODY OLIGONUCLEOTIDE CONJUGATES Yale University (US) 2025-12-03 EP claimed
CN-117050986-B CpG oligonucleotide with immune stimulating activity and its use 南京吉盛澳玛生物医药有限公司 2024-10-29 CN claimed
WO-2024158824-A1 ANTIBODY OLIGONUCLEOTIDE CONJUGATES YALE UNIVERSITY (US) 2024-08-02 WO claimed
CN-117050986-A CpG oligonucleotide with immune stimulating activity and its use 南京吉盛澳玛生物医药有限公司 2023-11-14 CN claimed
US-20230242916-A1 METHOD AND DRUG FOR TREATING HURLER SYNDROME EDIGENE THERAPEUTICS (BEIJING) INC. (CN) 2023-08-03 US claimed
US-20230242992-A1 METHODS OF PREDICTING CANCER PROGRESSION GMDX CO PTY LTD (AU) 2023-08-03 US claimed
CN-116529835-A Methods of predicting cancer progression GMDX私人有限公司 2023-08-01 CN claimed
EP-4158070-A1 METHODS OF PREDICTING CANCER PROGRESSION GMDx Co Pty Ltd (AU) 2023-04-05 EP claimed
WO-2021243401-A9 METHODS OF PREDICTING CANCER PROGRESSION GMDX CO PTY LTD (AU) 2023-02-23 WO claimed
CN-115697420-A Method and medicine for treating herler's syndrome 北京辑因医疗科技有限公司 2023-02-03 CN claimed
CN-114807153-A Multiple CpG oligodeoxynucleotide with immune stimulation activity and application thereof 南京吉盛澳玛生物医药有限公司 2022-07-29 CN claimed
CN-113528582-B Method and medicine for targeted editing of RNA based on LEAPER technology 博雅辑因(北京)生物科技有限公司 2022-05-17 CN claimed
US-12637713-B2 Methods and systems for phasing sequencing strands and long-range sequencing ULTIMA GENOMICS, INC. (US) 2026-05-26 US disclosed
US-20260139309-A1 METHODS AND SYSTEMS FOR EVALUATING MICROSATELLITE INSTABILITY STATUS Life Technologies Corporation (US) 2026-05-21 US disclosed
US-20260132458-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID MISMATCH ERROR DETECTION ULTIMA GENOMICS INC (US) 2026-05-14 US disclosed
US-20260112452-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID MISMATCH ERROR DETECTION APPLICATIONS ULTIMA GENOMICS INC (US) 2026-04-23 US disclosed
EP-1959919-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2008-08-27 EP disclosed
WO-2007068401-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2007-06-21 WO disclosed
US-6679761-B1 CHEMICAL MECHANICAL POLISHING; ABRASIVE GRAINS, A PEPTIDE, AN OXIDIZER SUSPENDED IN AQUEOUS MEDIUM SEIMI CHEMICAL CO., LTD. (JP) 2004-01-20 US disclosed
EP-1235261-A1 POLISHING COMPOUND FOR SEMICONDUCTOR CONTAINING PEPTIDE Seimi Chemical Co., Ltd. (JP) 2002-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637713-B2 Methods and systems for phasing sequencing strands and long-range sequencing POLQ, POLM, POLN PTGS1 2975/4885GSTK1 3584/4885ALDH1A1 4013/4885
US-20260112452-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID MISMATCH ERROR DETECTION APPLICATIONS DNMT3A, TRMT1L, METTL16 PTGS1 4555/4885GSTK1 4286/4885ALDH1A1 4109/4885
US-20260139309-A1 METHODS AND SYSTEMS FOR EVALUATING MICROSATELLITE INSTABILITY STATUS MSH2, PMS2, MSH6 PTGS1 4866/4885GSTK1 4120/4885ALDH1A1 4232/4885
US-20260132458-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID MISMATCH ERROR DETECTION UBE2V1, MCTS1, MICA PTGS1 4715/4885GSTK1 4348/4885ALDH1A1 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.