Sugi Predict

Sugi Predict / Compounds / SCHEMBL496680

SCHEMBL496680

SCHEMBL496680

c1ccc(CN2c3ccccc3Cc3ccccc32)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.61
▸ NOD1 Q9Y239 1/20 0.56
▸ HDAC6 Q9UBN7 3/20 0.52
▸ HDAC1 Q13547 2/20 0.52
▸ HDAC3 O15379 2/20 0.52
▸ RXFP1 Q9HBX9 1/20 0.52
▸ MEN1 O00255 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ APAF1 O14727 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ GAA P10253 2/20 0.49
▸ GFER P55789 1/20 0.49
▸ F2 P00734 1/20 0.48
▸ PLG P00747 1/20 0.48
▸ ELANE P08246 1/20 0.48
▸ CTSG P08311 1/20 0.48
▸ CMA1 P23946 1/20 0.48
▸ CTRC Q99895 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637973 1.00 POLB (0.61) POLBNOD1HDAC6HDAC1HDAC3
SCHEMBL29116691 0.86 NOD1 (0.73) POLBNOD1HDAC6HDAC1HDAC3
SCHEMBL29116672 0.85 LMNA (0.57) POLBNOD1HDAC6HDAC1HDAC3
SCHEMBL578257 0.85 POLB (0.73) POLBNOD1MEN1KMT2AALDH1A1
SCHEMBL30597487 0.85 POLB (0.73) POLBNOD1MEN1KMT2AALDH1A1
SCHEMBL11623661 0.84 HDAC1 (0.62) POLBNOD1HDAC6HDAC1HDAC3
SCHEMBL31310490 0.82 RXFP1 (0.63) POLBRXFP1MEN1KMT2AALDH1A1
SCHEMBL29827685 0.81 NOD1 (0.43) POLBNOD1HDAC6HDAC1HDAC3
SCHEMBL30144051 0.78 POLB (0.51) POLBNOD1RXFP1KMT2AALDH1A1
SCHEMBL20383138 0.78 HTR2A (0.53) NOD1HDAC6HDAC1HDAC3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
CN-115850170-A Acridine-10 (9H) - (3, 4, 5-trimethoxyphenyl) ketone compound and preparation method and application thereof 英维沃化工科技(广州)有限公司 2023-03-28 — — CN disclosed
CN-111018780-B N-carbonyl-9, 10-dihydroacridine compound and application thereof 南方医科大学 2022-12-02 — — CN disclosed
CN-109336813-B Photocatalytic oxidation synthesis method of acridone compounds 浙江工业大学上虞研究院有限公司 2021-08-10 — — CN disclosed
CN-111018780-A N-carbonyl-9, 10-dihydroacridine compound and application thereof 南方医科大学 2020-04-17 — — CN disclosed
CN-108912047-A The synthetic method of acridone derivatives 广州中医药大学(广州中医药研究院) 2018-11-30 — — CN disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
CN-107353890-A Polycyclic compound and the Organnic electroluminescent device including the polycyclic compound 三星显示有限公司 2017-11-17 — — CN disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-6858733-B2 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. (US) 2005-02-22 — — US disclosed
EP-1456176-A4 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN INC (US) 2004-11-03 — — EP disclosed
EP-1456176-A1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN, INC. (US) 2004-09-15 — — EP disclosed
US-20040176599-A1 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. 2004-09-09 — — US disclosed
US-20030232405-A1 Fluorescent detection of peroxidase enzymes LUMIGEN INC. 2003-12-18 — — US disclosed
WO-2003104447-A1 FLUORESCENT DETECTION OF PEROXIDASE ENZYMES LUMIGEN, INC. (US) 2003-12-18 — — WO disclosed
US-20030170762-A1 Compounds for generating chemiluminescence with a peroxidase LUMIGEN, INC. 2003-09-11 — — US disclosed
US-20030170771-A1 Compounds for generating chemiluminescence with a peroxidase AKHAVAN-TAFTI HASHEM (US) 2003-09-11 — — US disclosed
WO-2003053934-A1 IMPROVED COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE LUMIGEN, INC. (US) 2003-07-03 — — WO disclosed
US-4123347-A HYDROGEN DONOR SOLVENT EXXON RESEARCH & ENGINEERING CO. (US) 1978-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176599-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 POLB 532/4885NOD1 2429/4885HDAC6 4303/4885
US-20030170762-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 POLB 532/4885NOD1 2429/4885HDAC6 4303/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 POLB 2477/4885NOD1 1865/4885HDAC6 4858/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 POLB 2874/4885NOD1 859/4885HDAC6 3806/4885
US-20030170771-A1 Compounds for generating chemiluminescence with a peroxidase LPO, MPO, GPX4 POLB 532/4885NOD1 2429/4885HDAC6 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.