Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3108861 | 0.70 | PGK1 (0.41) | CTSSALDH1A1HPGD | |
| SCHEMBL27762078 | 0.70 | LMNA (0.43) | CTSSALDH1A1HPGD | |
| SCHEMBL3114802 | 0.68 | CTSK (0.55) | CTSS | |
| SCHEMBL4593268 | 0.65 | CYP11B1 (0.38) | CTSSSMN1; SMN2 | |
| SCHEMBL5022259 | 0.62 | CTSK (0.48) | CTSS | |
| SCHEMBL4593579 | 0.60 | REN (0.36) | ALDH1A1 | |
| SCHEMBL27823325 | 0.60 | CYP3A4 (0.41) | ALDH1A1HPGDRECQL | |
| SCHEMBL20226521 | 0.59 | KDM4E (0.36) | ALDH1A1HPGDRECQL | |
| SCHEMBL30971084 | 0.59 | MAPK8 (0.47) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27895277 | 0.58 | ALDH1A1 (0.40) | ALDH1A1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979351-A1 | 6-PHENYL-1H-IMIDAZO[4, 5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN K AND S INHIBITORS | N.V. Organon (NL) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007080191-A1 | 6-PHENYL-1H-IMIDAZO[4, 5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN K AND S INHIBITORS | N.V. ORGANON (NL) | 2007-07-19 | — | — | WO | disclosed |