Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821217 | 0.70 | S100A4 (0.33) | S100A4PTPRCBCHEACHECES1 | |
| SCHEMBL9218352 | 0.63 | — | — | |
| SCHEMBL11802296 | 0.63 | LMNA (0.33) | S100A4PTPRCBCHEACHECES1 | |
| SCHEMBL651428 | 0.52 | MEN1 (0.75) | ACHEHPGDTSHRHIF1A | |
| SCHEMBL1194020 | 0.51 | TSHR (0.45) | S100A4ACHECYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL30978214 | 0.49 | MEN1 (0.67) | ACHEHPGDTSHRHIF1A | |
| SCHEMBL1476442 | 0.49 | MEN1 (0.67) | ACHEHPGDTSHRHIF1A | |
| SCHEMBL136652 | 0.47 | — | — | |
| SCHEMBL9093617 | 0.47 | MEN1 (0.86) | HPGDTSHRHIF1A | |
| SCHEMBL14916717 | 0.47 | MEN1 (0.86) | HPGDTSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | claimed |
| US-9708350-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-18 | — | — | US | claimed |
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | disclosed |
| US-11066430-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| EP-3434713-B1 | METHODS OF PREPARING AND PURIFYING POLYALKYLENE GLYCOL DERIVATIVES | SHINETSU CHEMICAL CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10836861-B2 | Methods of preparing and purifying polyalkylene glycol derivative | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-10550136-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-02-04 | — | — | US | disclosed |
| US-10472377-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20190322688-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | SHINETSU CHEMICAL CO (JP) | 2019-10-24 | — | — | US | disclosed |
| US-20190315777-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | SHINETSU CHEMICAL CO (JP) | 2019-10-17 | — | — | US | disclosed |
| US-10377775-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| WO-2001030802-A2 | THERAPEUTIC TREATMENTS COMPRISING ADMINISTRATION OF CERTAIN STEROIDS FOR BLOOD CELL DEFICIENCIES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
| WO-2000032201-A2 | USE OF 17-KETOSTEROIDS FOR THE TREATMENT OF MALARIA AND TRYPANOSOMIASIS | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000032176-A2 | USE OF 17-KETOSTEROIDS FOR THE TREATMENT OF TOXOPLASMOSIS AND CRYPTOSPORIDOSIS | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000032177-A2 | USE OF 17-KETOSTEROIDS IN THE TREATMENT OF HEPATITIS C VIRUS AND OTHER TOGAVIRUS INFECTIONS | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| US-6034118-A | ENZYME INHIBITOR | GILEAD SCIENCES, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5811450-A | DIAGNOSIS, TREATMENT OF HIV | GILEAD SCIENCES, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705524-A | ENZYME INHIBITORS; VIRICIDES | GILEAD SCIENCES, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| EP-0789695-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014314-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1996-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377775-B2 | Method for producing polyalkylene glycol derivative having amino group at end | KCNMA1, KCNMB1, KCNMB4 | S100A4 1604/4885PTPRC 4518/4885BCHE 4099/4885 |
| US-11066430-B2 | Method for producing polyalkylene glycol derivative having amino group at end | RAD1, AP3B1, RER1 | S100A4 1674/4885PTPRC 4464/4885BCHE 3557/4885 |
| US-10472377-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | ADH1A, ADH1C, AP3M1 | S100A4 2972/4885PTPRC 4536/4885BCHE 3148/4885 |
| US-10550136-B2 | Method for producing polyalkylene glycol derivative having amino group at end | RAD1, AP3B1, RER1 | S100A4 1702/4885PTPRC 4452/4885BCHE 3577/4885 |
| US-20190315777-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | KCNMA1, KCNMB1, KCNMB4 | S100A4 1623/4885PTPRC 4512/4885BCHE 4115/4885 |
| US-20190322688-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | RAD1, AP3B1, RER1 | S100A4 1674/4885PTPRC 4464/4885BCHE 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.