SCHEMBL4986973

SCHEMBL4986973

CCOCC(C)(COCC)COCC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017804 0.88
SCHEMBL10447692 0.87 TSHR (0.33) ALDH1A1
SCHEMBL1561949 0.87 TSHR (0.33) ALDH1A1
SCHEMBL23905705 0.82
SCHEMBL18961181 0.82 ALDH1A1 (0.39) ALDH1A1
SCHEMBL938000 0.82 LMNA (0.46)
SCHEMBL15096043 0.80 MEN1 (0.38) ALDH1A1
SCHEMBL21914175 0.80 MEN1 (0.33) ALDH1A1
SCHEMBL9192589 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1276341 0.79 TSHR (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209223-A1 CATIONIC UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2024-06-27 US disclosed
US-20230357776-A1 COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2023-11-09 US disclosed
US-11732265-B2 Compositions and methods for modulating complement factor B expression IONIS PHARMACEUTICALS, INC. (US) 2023-08-22 US disclosed
US-20230151365-A1 COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2023-05-18 US disclosed
US-9714421-B2 Compositions and methods IONIS PHARMACEUTICALS, INC. (US) 2017-07-25 US disclosed
US-20170183661-A1 COMPOSITIONS AND METHODS FOR MODULATING PKK EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2017-06-29 US disclosed
US-20170166899-A1 COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2017-06-15 US disclosed
US-20170159055-A1 COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2017-06-08 US disclosed
US-20160354476-A1 TARGETED THERAPEUTIC NUCLEOSIDES AND THEIR USE IONIS PHARMACEUTICALS, INC. (US) 2016-12-08 US disclosed
US-20160194349-A1 COMPOSITIONS AND METHODS FOR MODULATING ANGIOPOIETIN-LIKE 3 EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2016-07-07 US disclosed
US-20150176007-A1 COMPOSITIONS AND METHODS FOR MODULATING HBV EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2015-06-25 US disclosed
US-20150126719-A1 COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2015-05-07 US disclosed
US-20150126718-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2015-05-07 US disclosed
US-20150126720-A1 COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2015-05-07 US disclosed
US-20140343123-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE ISIS PHARMACEUTICALS, INC. (US) 2014-11-20 US disclosed
US-7368516-B2 Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst TOSOH CORPORATION (JP) 2008-05-06 US disclosed
US-20050187419-A1 Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst TOSOH CORPORATION (JP) 2005-08-25 US disclosed
US-6900152-B2 Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst TOSOH CORPORATION (JP) 2005-05-31 US disclosed
US-20020035029-A1 Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst TOSOH CORPORATION (JP) 2002-03-21 US disclosed
US-6337297-B1 CHROMIUM CATALYST FOR TRIMERIZATION OF ETHYLENE WITH MULTIDENTATE LIGAND OR HALOGEN, CARBOXY GROUP TOSOH CORPORATION (JP) 2002-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160354476-A1 TARGETED THERAPEUTIC NUCLEOSIDES AND THEIR USE FUT6, GALNT6, FUT5 ALDH1A1 1445/4885
US-20050187419-A1 Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst ACMSD, TAF9, ETV6 ALDH1A1 2843/4885
US-20230151365-A1 COMPOSITIONS AND METHODS FOR MODULATING TTR EXPRESSION TTR, GALNT1, GALNT3 ALDH1A1 1286/4885
US-20160194349-A1 COMPOSITIONS AND METHODS FOR MODULATING ANGIOPOIETIN-LIKE 3 EXPRESSION TEK, PLIN3, FABP3 ALDH1A1 2808/4885
US-20150176007-A1 COMPOSITIONS AND METHODS FOR MODULATING HBV EXPRESSION HAVCR2, HCCS, HDGF ALDH1A1 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.